SCHEMBL7187326

SCHEMBL7187326

CCCCc1cccc(C=O)c1O[SiH](C)C

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
LIPG Q9Y5X9 1/20 0.34
ALOX5 P09917 1/20 0.34
PTGS2 P35354 1/20 0.34
PPARA Q07869 3/20 0.33
BID P55957 5/20 0.33
MCL1 Q07820 5/20 0.33
BCL2L1 Q07817 4/20 0.33
BAK1 Q16611 4/20 0.33
KAT8 Q9H7Z6 2/20 0.33
PPARG P37231 2/20 0.33
SAE1 Q9UBE0 2/20 0.33
THRA P10827 1/20 0.33
THRB P10828 1/20 0.33
PIM1 P11309 1/20 0.33
PIM3 Q86V86 1/20 0.33
EP300 Q09472 1/20 0.33
KAT2A Q92830 1/20 0.33
KAT2B Q92831 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5223765 0.83 CA1 (0.51) CA1CA2LIPGALOX5PTGS2
SCHEMBL27775346 0.82 GAA (0.41) CA1CA2LIPGALOX5PTGS2
SCHEMBL8119443 0.78 LMNA (0.45) CA1CA2LIPGPPARACYP2C9
SCHEMBL19383789 0.78 CA1 (0.40) CA1CA2LIPGALOX5PTGS2
SCHEMBL28321749 0.78 PPARA (0.49) CA1CA2LIPGALOX5PTGS2
SCHEMBL18394129 0.78 LIPG (0.45) CA1CA2LIPGALOX5PTGS2
SCHEMBL6585065 0.77 ALOX5 (0.36) LIPGALOX5PTGS2PPARABID
SCHEMBL5074490 0.77 BID (0.44) ALOX5PTGS2PPARABIDMCL1
SCHEMBL2288674 0.77 PTGER4 (0.42) CA1CA2LIPGALOX5PTGS2
SCHEMBL266417 0.76 LIPG (0.47) LIPGTHRATHRBCYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003024909-A1 METHOD OF PREPARING SYMMETRICAL POLYHYDROXYSTILBENES L'OREAL (FR) 2003-03-27 WO disclosed