Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7187330 | 1.00 | TSHR (0.38) | TSHRALDH1A1LMNAL3MBTL1LTA4H | |
| SCHEMBL1874566 | 0.88 | CNR2 (0.40) | TSHRALDH1A1PPARGPPARDPPARA | |
| SCHEMBL10300852 | 0.88 | CNR2 (0.40) | TSHRALDH1A1PPARGPPARDPPARA | |
| SCHEMBL1874564 | 0.88 | CNR2 (0.40) | TSHRALDH1A1PPARGPPARDPPARA | |
| SCHEMBL8800095 | 0.86 | L3MBTL1 (0.43) | ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL6128459 | 0.84 | ADORA3 (0.37) | TSHRALDH1A1L3MBTL1LTA4HPPARG | |
| SCHEMBL28543675 | 0.81 | TSHR (0.38) | TSHRALDH1A1LMNAPPARGPPARD | |
| SCHEMBL6128466 | 0.81 | ALDH1A1 (0.35) | TSHRALDH1A1LMNA | |
| SCHEMBL8517154 | 0.81 | ALDH1A1 (0.35) | TSHRALDH1A1LMNA | |
| SCHEMBL24438525 | 0.79 | ALDH1A1 (0.47) | TSHRALDH1A1LMNAL3MBTL1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6646106-B1 | Polymerizing chiral diphosphine having a C2 axis of symmetry, with one or several polymerizable monomers, said chiral diphosphine consisting of a chiral body bearing two identical functional groups | RHODIA CHIMIE (FR) | 2003-11-11 | — | — | US | disclosed |