Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12431305 | 0.90 | TDP1 (0.61) | TDP1ALDH1A1POLBHPGDSMN1; SMN2 | |
| SCHEMBL4168384 | 0.88 | ALDH1A1 (0.56) | TDP1ALDH1A1POLBHPGDSMN1; SMN2 | |
| SCHEMBL7192635 | 0.87 | SLC1A3 (0.61) | ALDH1A1HPGDSMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL29131169 | 0.87 | TDP1 (0.61) | TDP1ALDH1A1POLBHPGDSMN1; SMN2 | |
| SCHEMBL7188387 | 0.87 | MAPT (0.57) | ALDH1A1POLBHPGDSMN1; SMN2MAOA | |
| SCHEMBL4436251 | 0.86 | CYP1A2 (0.52) | ALDH1A1HPGDSMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL6099338 | 0.83 | SLC2A1 (0.54) | TDP1ALDH1A1SMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL11244788 | 0.80 | TDP1 (0.87) | TDP1ALDH1A1POLBHPGDSMN1; SMN2 | |
| SCHEMBL3731505 | 0.79 | TDP1 (0.51) | TDP1ALDH1A1POLBHPGDSMN1; SMN2 | |
| SCHEMBL61417 | 0.78 | TDP1 (1.00) | TDP1ALDH1A1POLBHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6566546-B2 | Reacting of phenylboronic acids with 4- bromo- or 4-iodo-alkyl- or -alkoxy-anilines or -anilides, possible deacylation and diazotization, followed by reaction with a nucleophile by sandmeyer reaction or a reducing agent | CLARIANT GMBH (DE) | 2003-05-20 | — | — | US | disclosed |
| US-20020115880-A1 | PROCESS FOR PREPARING 4-SUBSTITUTED 2-ALKYLBIPHENYLS AND 2-ALKOXYLBIPHENYLS | CLARIANT GMBH | 2002-08-22 | — | — | US | disclosed |
| EP-1233009-A2 | Method for production of 4-substituted 2-alkylbiphenyls and 2-alcoxybiphenyls | Clariant GmbH (DE) | 2002-08-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020115880-A1 | PROCESS FOR PREPARING 4-SUBSTITUTED 2-ALKYLBIPHENYLS AND 2-ALKOXYLBIPHENYLS | ARSA, ALKBH2, ALKBH1 | TDP1 3780/4885ALDH1A1 540/4885POLB 865/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.