Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 19/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 17/20 | 0.47 |
| ▸ | TOP2A | P11388 | 1/20 | 0.38 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7182784 | 0.91 | ESR1 (0.46) | ESR1ESR2 | |
| SCHEMBL7183659 | 0.88 | ESR1 (0.54) | ESR1ESR2 | |
| SCHEMBL7182700 | 0.88 | ALDH1A1 (0.43) | ESR1ESR2 | |
| SCHEMBL7188433 | 0.85 | ESR1 (0.48) | ESR1ESR2 | |
| SCHEMBL8499330 | 0.84 | ESR1 (0.53) | ESR1ESR2 | |
| SCHEMBL7187252 | 0.84 | ESR1 (0.62) | ESR1ESR2 | |
| SCHEMBL7189109 | 0.82 | ESR1 (0.48) | ESR1ESR2 | |
| SCHEMBL7186036 | 0.82 | ESR1 (0.49) | ESR1ESR2 | |
| SCHEMBL7190578 | 0.81 | ESR1 (0.51) | ESR1ESR2 | |
| SCHEMBL7191690 | 0.81 | ESR1 (0.54) | ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0835867-B1 | 1-Aryloxy-2-arylnaphthyl compounds, intermediates, compositions, and methods | LILLY CO ELI (US) | 2003-12-03 | — | — | EP | claimed |