SCHEMBL7187841

SCHEMBL7187841

Cc1ccccc1Oc1ccccc1S(=O)(=O)c1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 5/20 0.64
CASP1 P29466 2/20 0.50
SMN1; SMN2 Q16637 4/20 0.43
LMNA P02545 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
KMT2A Q03164 4/20 0.42
MEN1 O00255 2/20 0.42
TSHR P16473 2/20 0.42
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
HTT P42858 2/20 0.41
HSD11B1 P28845 1/20 0.41
HPGD P15428 1/20 0.41
ALDH1A1 P00352 1/20 0.40
POLB P06746 1/20 0.40
MAPT P10636 1/20 0.40
BCAT1 P54687 1/20 0.39
MMP2 P08253 1/20 0.39
MMP3 P08254 1/20 0.39
MMP9 P14780 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8741343 0.89 CASP1 (0.51) HTR6CASP1SMN1; SMN2LMNAKMT2A
Biphenyl SCHEMBL28423764 0.84 HTR6 (0.65) HTR6CASP1SMN1; SMN2LMNANPSR1
SCHEMBL9323437 0.80 HTR6 (0.65) HTR6CASP1SMN1; SMN2LMNAKMT2A
SCHEMBL10342789 0.79 HTR6 (0.65) HTR6KMT2ATSHRHTTHPGD
SCHEMBL31092469 0.79 HTR6 (0.57) HTR6SMN1; SMN2KMT2AMEN1TSHR
SCHEMBL1713160 0.79 HTR6 (0.57) HTR6SMN1; SMN2KMT2AMEN1TSHR
SCHEMBL5682949 0.79 CASP1 (0.49) HTR6CASP1SMN1; SMN2LMNAKMT2A
SCHEMBL7090901 0.79 CASP1 (0.52) CASP1SMN1; SMN2KMT2AMEN1TSHR
SCHEMBL3877578 0.79 CASP1 (0.49) CASP1SMN1; SMN2KMT2AMEN1TSHR
SCHEMBL6913555 0.78 HTR6 (1.00) HTR6KMT2AMMP2MMP8MMP12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030054184-A1 Optical element, method for the production thereof and optical module HITACHI CHEMICAL CO., LTD. (JP) 2003-03-20 US disclosed