Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.50 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.48 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 9/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | PTGES | O14684 | 2/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 6/20 | 0.39 |
| ▸ | PPARD | Q03181 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7193900 | 0.95 | MTNR1A (0.47) | MTNR1AMTNR1BSLC5A1SLC5A2PPARG | |
| SCHEMBL7194895 | 0.93 | LTB4R (0.46) | MTNR1AMTNR1BSLC5A1SLC5A2PPARG | |
| SCHEMBL7197666 | 0.93 | MTNR1A (0.50) | MTNR1AMTNR1BSLC5A1SLC5A2PPARG | |
| SCHEMBL7193929 | 0.92 | LTB4R (0.47) | MTNR1AMTNR1BPPARGPTGESALOX5 | |
| SCHEMBL7195798 | 0.88 | MTNR1A (0.47) | MTNR1AMTNR1BSLC5A1SLC5A2PPARG | |
| SCHEMBL7196332 | 0.86 | SLC5A1 (0.44) | MTNR1AMTNR1BSLC5A1SLC5A2L3MBTL1 | |
| SCHEMBL7194746 | 0.86 | MTNR1A (0.44) | MTNR1AMTNR1BSLC5A1SLC5A2L3MBTL1 | |
| SCHEMBL7197695 | 0.85 | LTB4R (0.46) | MTNR1AMTNR1BSLC5A1SLC5A2PPARG | |
| SCHEMBL7194227 | 0.85 | MTNR1A (0.48) | MTNR1AMTNR1BSLC5A1SLC5A2L3MBTL1 | |
| SCHEMBL7198836 | 0.84 | LTB4R (0.47) | MTNR1AMTNR1BPPARGPTGESALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030065039-A1 | Biologically active 1,3-bis-aromatic-prop-2-en-1-ones, 1,3-bis-aromatic-propan-1-ones, and 1,3-bis-aromatic-prop-2-yn-1-ones | STATENS SERUM INSTITUTE (DK) | 2003-04-03 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030065039-A1 | Biologically active 1,3-bis-aromatic-prop-2-en-1-ones, 1,3-bis-aromatic-propan-1-ones, and 1,3-bis-aromatic-prop-2-yn-1-ones | AKR1C3, AKR1C1, AKR1A1 | MTNR1A 2653/4885MTNR1B 3284/4885SLC5A1 3292/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.