Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A1 | P13866 | 2/20 | 0.44 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7192835 | 0.94 | SLC5A1 (0.41) | SLC5A1SLC5A2MTNR1AMTNR1BSMN1; SMN2 | |
| SCHEMBL7193435 | 0.93 | LTB4R (0.45) | SLC5A1SLC5A2SMN1; SMN2L3MBTL1LMNA | |
| SCHEMBL7193964 | 0.93 | SLC5A1 (0.44) | SLC5A1SLC5A2MTNR1AMTNR1BSMN1; SMN2 | |
| SCHEMBL7192437 | 0.92 | LTB4R (0.47) | SMN1; SMN2L3MBTL1LTB4RMAPTAPAF1 | |
| SCHEMBL7190531 | 0.89 | SLC5A1 (0.45) | SLC5A1SLC5A2MTNR1AMTNR1BSMN1; SMN2 | |
| SCHEMBL7199059 | 0.88 | SLC5A1 (0.42) | SLC5A1SLC5A2MTNR1AMTNR1BAKT1 | |
| SCHEMBL7195025 | 0.87 | SLC5A1 (0.41) | SLC5A1SLC5A2MTNR1AMTNR1BSMN1; SMN2 | |
| SCHEMBL7188087 | 0.86 | MTNR1A (0.50) | SLC5A1SLC5A2MTNR1AMTNR1BL3MBTL1 | |
| SCHEMBL7196497 | 0.86 | LTB4R (0.45) | SLC5A1SLC5A2SMN1; SMN2L3MBTL1LMNA | |
| SCHEMBL7187189 | 0.85 | LTB4R (0.47) | SMN1; SMN2L3MBTL1LTB4RMAPTAPAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030065039-A1 | Biologically active 1,3-bis-aromatic-prop-2-en-1-ones, 1,3-bis-aromatic-propan-1-ones, and 1,3-bis-aromatic-prop-2-yn-1-ones | STATENS SERUM INSTITUTE (DK) | 2003-04-03 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030065039-A1 | Biologically active 1,3-bis-aromatic-prop-2-en-1-ones, 1,3-bis-aromatic-propan-1-ones, and 1,3-bis-aromatic-prop-2-yn-1-ones | AKR1C3, AKR1C1, AKR1A1 | SLC5A1 3292/4885SLC5A2 4543/4885MTNR1A 2653/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.