SCHEMBL7188795

SCHEMBL7188795

Cc1cc(N)cc(S(=O)(=O)c2ccc(N)c(C)c2)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.47
HTR6 P50406 4/20 0.47
PKM P14618 1/20 0.47
LMNA P02545 3/20 0.43
GAA P10253 2/20 0.41
MAPT P10636 2/20 0.41
TSHR P16473 3/20 0.40
RAPGEF4 Q8WZA2 4/20 0.40
CYP3A4 P08684 3/20 0.40
TDP1 Q9NUW8 3/20 0.40
MPO P05164 1/20 0.39
CYP2C9 P11712 1/20 0.39
NPC1 O15118 1/20 0.37
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA4 P22748 1/20 0.37
CA6 P23280 1/20 0.37
CA5A P35218 1/20 0.37
CA7 P43166 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL436337 0.86 ALDH1A1 (0.55) ALDH1A1HTR6PKMLMNAGAA
SCHEMBL7194387 0.84 ALDH1A1 (0.57) ALDH1A1HTR6PKMLMNAGAA
SCHEMBL7192574 0.82 HTR6 (0.61) ALDH1A1HTR6PKMLMNAGAA
SCHEMBL7194320 0.82 ALDH1A1 (0.69) ALDH1A1HTR6PKMLMNAGAA
SCHEMBL7185483 0.81 LMNA (0.69) ALDH1A1HTR6PKMLMNAGAA
SCHEMBL7187584 0.79 LMNA (0.71) ALDH1A1HTR6PKMLMNAMAPT
SCHEMBL13783389 0.79 ALDH1A1 (0.53) ALDH1A1HTR6PKMLMNAGAA
SCHEMBL7136138 0.79 PKM (0.47) ALDH1A1HTR6PKMGAAMAPT
SCHEMBL11947067 0.78 TDP1 (0.55) ALDH1A1PKMLMNAGAAMAPT
SCHEMBL7138688 0.76 HTR6 (0.70) ALDH1A1HTR6PKMLMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030064235-A1 Optical members made of polymide resins MITSUI CHEMICALS, INC. (JP) 2003-04-03 US disclosed
EP-1237015-A1 OPTICAL MEMBERS MADE OF POLYIMIDE RESINS Mitsui Chemicals, Inc. (JP) 2002-09-04 EP disclosed