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SCHEMBL7189042

SCHEMBL7189042

Cc1cc(C)c(C(=O)P(=O)(C(=O)c2c(C(C)(C)C)cc(C(C)(C)C)cc2C(C)(C)C)c2ccccc2)c(C)c1C

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 3/20 0.35
▸ KMT2A Q03164 3/20 0.35
▸ GAA P10253 1/20 0.35
▸ ALDH1A1 P00352 5/20 0.34
▸ ALOX5 P09917 2/20 0.34
▸ PTGS2 P35354 2/20 0.34
▸ NPSR1 Q6W5P4 1/20 0.34
▸ LMNA P02545 2/20 0.33
▸ KDM4E B2RXH2 2/20 0.32
▸ HPGD P15428 1/20 0.32
▸ CYP1A2 P05177 1/20 0.32
▸ CYP3A4 P08684 1/20 0.32
▸ CYP2C9 P11712 1/20 0.32
▸ TSHR P16473 1/20 0.32
▸ CYP2C19 P33261 1/20 0.32
▸ RXRB P28702 2/20 0.32
▸ RARA P10276 1/20 0.31
▸ RXRA P19793 1/20 0.31
▸ RXRG P48443 1/20 0.31
▸ MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7175877 0.92 ALDH1A1 (0.37) MEN1KMT2AGAAALDH1A1LMNA
SCHEMBL7183900 0.91 MEN1 (0.39) MEN1KMT2AGAAALDH1A1ALOX5
SCHEMBL7189845 0.88 LMNA (0.37) MEN1KMT2AGAAALOX5PTGS2
SCHEMBL7181473 0.86 NPSR1 (0.39) MEN1KMT2AGAAALDH1A1ALOX5
SCHEMBL7190426 0.86 ALDH1A1 (0.38) MEN1KMT2AGAAALDH1A1LMNA
SCHEMBL7181616 0.85 KMT2A (0.36) MEN1KMT2AGAAALDH1A1LMNA
SCHEMBL7179675 0.84 LMNA (0.37) MEN1KMT2AGAAALDH1A1LMNA
SCHEMBL7187514 0.84 LMNA (0.40) MEN1KMT2AGAAALDH1A1NPSR1
SCHEMBL7180464 0.83 KMT2A (0.34) MEN1KMT2AGAAALDH1A1LMNA
SCHEMBL7174855 0.83 GFER (0.35) MEN1KMT2AGAAALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6579663-B2 Chemical intermediates such as lithium 2,6-dimethylbenzoyl phenylphosphine for preparation of acylphosphines, acylphosphine oxides or acylphosphine sulfides CIBA SPECIALTY CHEMICALS CORPORATION 2003-06-17 — — US disclosed
US-20020107413-A1 Organometallic monoacylarylphosphines WOLF JEAN-PIERRE (CH) 2002-08-08 — — US disclosed
US-6399805-B2 SUCH AS LITHIUM 2,6-DIMETHYLBENZOYLPHENYLPHOSPHINE, USE AS PHOTOINITIATORS IN PHOTOCURABLE COMPOSITIONS SUCH AS FOR PHOTOGRAPHIC PRODUCTION OF RELIEF IMAGES CIBA SPECIALTY CHEMICALS CORPORATION 2002-06-04 — — US disclosed
US-20010031898-A1 Organometallic monoacylarylphosphines CIBA SPECIALTY CHEMICALS CORP. 2001-10-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020107413-A1 Organometallic monoacylarylphosphines CBR1, NAF1, DHCR24 MEN1 2312/4885KMT2A 1586/4885GAA 4753/4885
US-20010031898-A1 Organometallic monoacylarylphosphines NAF1, DHCR24, CBR1 MEN1 2263/4885KMT2A 956/4885GAA 4793/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.