Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7182700 | 0.93 | ALDH1A1 (0.43) | L3MBTL1ALDH1A1KMT2AMEN1HSD17B10 | |
| SCHEMBL7182784 | 0.89 | ESR1 (0.46) | ESR1ESR2FFAR1FFAR4 | |
| SCHEMBL7193820 | 0.89 | ALOX5 (0.42) | LMNAL3MBTL1MAPTALDH1A1GAA | |
| SCHEMBL7187213 | 0.86 | FFAR4 (0.47) | LMNAMAPTALDH1A1HSD17B10KDM4E | |
| SCHEMBL8497879 | 0.85 | KMT2A (0.42) | LMNAMAPTALDH1A1GRM2KMT2A | |
| SCHEMBL7189250 | 0.83 | ESR1 (0.43) | LMNAMAPTKDM4ENPC1TP53 | |
| SCHEMBL7189999 | 0.82 | CYP4F2 (0.46) | LMNAL3MBTL1MAPTALDH1A1GAA | |
| SCHEMBL7188063 | 0.82 | ESR1 (0.44) | KMT2AMEN1MAOAALOX5ESR1 | |
| SCHEMBL7183632 | 0.82 | FFAR1 (0.52) | LMNAMAPTALDH1A1HSD17B10KDM4E | |
| SCHEMBL7191941 | 0.82 | HPGD (0.46) | ALDH1A1KMT2AKDM4ECYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0835867-B1 | 1-Aryloxy-2-arylnaphthyl compounds, intermediates, compositions, and methods | LILLY CO ELI (US) | 2003-12-03 | — | — | EP | claimed |