Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 10/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6790513 | 0.85 | OPRD1 (0.97) | OPRD1KMT2AMEN1OPRM1OPRK1 | |
| SCHEMBL6792134 | 0.80 | OPRD1 (0.63) | OPRD1KMT2AMEN1ALDH1A1KDM4E | |
| Carbamic Acid SCHEMBL17460399 | 0.78 | KMT2A (0.68) | OPRD1KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL5267415 | 0.78 | CYP2D6 (0.68) | OPRD1KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL15166138 | 0.77 | OPRD1 (0.60) | OPRD1KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL6791709 | 0.77 | OPRD1 (1.00) | OPRD1OPRM1OPRK1 | |
| SCHEMBL2433276 | 0.76 | SLC6A2 (0.53) | OPRD1KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL6011755 | 0.76 | OPRD1 (0.58) | OPRD1ALDH1A1KDM4EMAPTSLC6A2 | |
| SCHEMBL22227819 | 0.76 | SLC6A2 (0.56) | OPRD1MAPTHPGDSLC6A2SLC6A4 | |
| SCHEMBL20832766 | 0.76 | SLC6A2 (0.56) | OPRD1MAPTHPGDSLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6583177-B2 | Amidinophenol derivatives as leukotriene B4 (LTB4)antagonists, phospholipase A2 inhibitors, and trypsin inhibitors. | ONO PHARMACEUTICAL CO., LTD. (JP) | 2003-06-24 | — | — | US | disclosed |
| US-20020128315-A1 | Leukotriene B4 antagonist compounds and method for treatment | NAKAI HISAO (JP) | 2002-09-12 | — | — | US | disclosed |
| US-6262114-B1 | NOVEL AMIDINOPHENOL DERIVATIVES; INHIBITORS OF PHOSPHOLIPASE A2 AND/OR TRYPSIN | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-07-17 | — | — | US | disclosed |
| EP-0703216-B1 | Amidinophenol derivatives as protease inhibitors | ONO PHARMACEUTICAL CO (JP) | 1999-04-07 | — | — | EP | disclosed |
| EP-0703216-A1 | Amidinophenol derivatives as protease inhibitors | ONO PHARMACEUTICAL CO., LTD. (JP) | 1996-03-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020128315-A1 | Leukotriene B4 antagonist compounds and method for treatment | LTB4R2, LTB4R, LTA4H | OPRD1 2610/4885KMT2A 3478/4885MEN1 4125/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.