SCHEMBL9909848

SCHEMBL9909848

Oc1cc(P(c2ccccc2)c2ccccc2)c(O)cc1P(c1ccccc1)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.52
CYP3A4 P08684 2/20 0.52
ESR1 P03372 4/20 0.52
ESR2 Q92731 4/20 0.52
DRD1 P21728 2/20 0.40
BACE1 P56817 1/20 0.39
KDM4E B2RXH2 3/20 0.37
GAA P10253 2/20 0.37
ALOX15 P16050 3/20 0.36
ALDH1A1 P00352 3/20 0.36
HPGD P15428 3/20 0.36
HSD17B10 Q99714 3/20 0.36
LMNA P02545 2/20 0.36
MAPT P10636 2/20 0.36
CA12 O43570 2/20 0.36
CA2 P00918 2/20 0.36
CA3 P07451 2/20 0.36
CA4 P22748 2/20 0.36
CA14 Q9ULX7 2/20 0.36
NPC1 O15118 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13840654 0.88 CYP3A4 (0.45) TDP1CYP3A4ESR1ESR2DRD1
SCHEMBL27649372 0.82 ESR1 (0.45) TDP1CYP3A4ESR1ESR2DRD1
SCHEMBL3679308 0.82 ESR2 (0.56) TDP1CYP3A4ESR1ESR2KDM4E
SCHEMBL29543525 0.82 ESR2 (0.56) TDP1CYP3A4ESR1ESR2KDM4E
SCHEMBL25176323 0.82 ESR2 (0.56) TDP1CYP3A4ESR1ESR2DRD1
SCHEMBL2551265 0.80 TDP1 (0.52) TDP1CYP3A4ESR1ESR2DRD1
SCHEMBL30759711 0.80 TDP1 (0.52) TDP1CYP3A4ESR1ESR2DRD1
SCHEMBL28402531 0.79 THRB (0.47) TDP1CYP3A4ESR1ESR2KDM4E
SCHEMBL7189644 0.79 ALOX15 (0.45) TDP1CYP3A4ESR1ESR2KDM4E
SCHEMBL12265492 0.79 HSD17B10 (0.45) TDP1CYP3A4ESR1ESR2ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9029541-B2 Binuclear metal complex, and organic electroluminescence element comprising same UBE INDUSTRIES, LTD. (JP) 2015-05-12 US disclosed
US-9029541-B2 Binuclear metal complex, and organic electroluminescence element comprising same UBE INDUSTRIES, LTD. (JP) 2015-05-12 US disclosed
US-20130324733-A1 BINUCLEAR METAL COMPLEX, AND ORGANIC ELECTROLUMINESCENCE ELEMENT COMPRISING SAME UBE INDUSTRIES, LTD. (JP) 2013-12-05 US disclosed
EP-2647642-A1 BINUCLEAR METAL COMPLEX, AND ORGANIC ELECTROLUMINESCENCE ELEMENT USING SAME Ube Industries, Ltd. (JP) 2013-10-09 EP disclosed
EP-2647642-A1 BINUCLEAR METAL COMPLEX, AND ORGANIC ELECTROLUMINESCENCE ELEMENT USING SAME Ube Industries, Ltd. (JP) 2013-10-09 EP disclosed
WO-2012074111-A1 BINUCLEAR METAL COMPLEX, AND ORGANIC ELECTROLUMINESCENCE ELEMENT USING SAME 宇部興産株式会社 (JP) 2012-06-07 WO disclosed