Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1610054 | 0.82 | TUBB1 (0.41) | TUBB1 | |
| SCHEMBL15370277 | 0.79 | SRC (0.41) | TUBB1 | |
| SCHEMBL10018816 | 0.74 | ALDH1A1 (0.46) | — | |
| SCHEMBL11041539 | 0.74 | APEX1 (0.45) | — | |
| SCHEMBL10871325 | 0.71 | ALDH1A1 (0.50) | TUBB1 | |
| SCHEMBL15370274 | 0.70 | EGFR (0.57) | — | |
| SCHEMBL12659277 | 0.70 | KDM4E (0.54) | — | |
| SCHEMBL459156 | 0.69 | RAPGEF4 (0.39) | — | |
| SCHEMBL5780229 | 0.69 | AHR (0.44) | — | |
| SCHEMBL10551448 | 0.67 | CA1 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6583179-B2 | For therapy of uterine fibroids, endometriosis, polycystic ovarian disease, dysfunctional uterine bleeding, breast cancer and ovarian cancer; depletion of oocytes; spermatocyte depletion; for female and male contraception | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2003-06-24 | — | — | US | disclosed |