SCHEMBL7190095

SCHEMBL7190095

Nc1ccc(Oc2ccc(Br)c(Oc3ccc(N)cc3)c2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.57
ALDH1A1 P00352 8/20 0.56
TDP1 Q9NUW8 2/20 0.56
CYP3A4 P08684 1/20 0.56
TSHR P16473 1/20 0.56
SMN1; SMN2 Q16637 3/20 0.55
MEN1 O00255 3/20 0.55
KMT2A Q03164 3/20 0.55
MITF O75030 1/20 0.55
GAA P10253 1/20 0.55
GFER P55789 1/20 0.55
NLRP1 Q9C000 1/20 0.55
NOD2 Q9HC29 1/20 0.55
MAOA P21397 2/20 0.48
MAOB P27338 2/20 0.47
TEAD4 Q15561 1/20 0.47
POLB P06746 1/20 0.45
MAPK1 P28482 2/20 0.44
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9629857 0.86 MAPT (0.61) MAPTALDH1A1TDP1CYP3A4TSHR
SCHEMBL9630121 0.82 MAPT (0.54) MAPTALDH1A1TDP1CYP3A4TSHR
SCHEMBL16890039 0.82 LTA4H (0.50) MAPTALDH1A1TSHRSMN1; SMN2MEN1
SCHEMBL29535209 0.81 ALDH1A1 (0.64) MAPTALDH1A1TDP1CYP3A4TSHR
SCHEMBL28718997 0.81 ALDH1A1 (0.64) MAPTALDH1A1TDP1CYP3A4TSHR
SCHEMBL5034696 0.78 MAOA (0.52) MAPTALDH1A1TDP1CYP3A4TSHR
SCHEMBL31287823 0.78 MAPT (0.55) MAPTALDH1A1TDP1CYP3A4TSHR
SCHEMBL31287745 0.78 MAPT (0.55) MAPTALDH1A1TDP1CYP3A4TSHR
SCHEMBL7190064 0.78 MAPT (0.54) MAPTALDH1A1TDP1CYP3A4TSHR
SCHEMBL29520889 0.78 NCOA1 (0.56) MAPTALDH1A1TDP1CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030064235-A1 Optical members made of polymide resins MITSUI CHEMICALS, INC. (JP) 2003-04-03 US disclosed
EP-1237015-A1 OPTICAL MEMBERS MADE OF POLYIMIDE RESINS Mitsui Chemicals, Inc. (JP) 2002-09-04 EP disclosed