Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.41 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.41 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.41 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.41 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.41 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7200688 | 0.85 | TUBB1 (0.45) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL8460294 | 0.81 | AKR1B1 (0.39) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL7187364 | 0.79 | ALOX5 (0.40) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL13063307 | 0.74 | CYP19A1 (0.42) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL17807469 | 0.74 | AXL (0.46) | MAPTTSHRALDH1A1RXFP1NPSR1 | |
| SCHEMBL7196530 | 0.71 | MAPT (0.47) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL27631190 | 0.71 | ACHE (0.50) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL7194516 | 0.70 | GPR55 (0.47) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL2633152 | 0.69 | PTGES (0.49) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1505362 | 0.68 | MAPT (0.52) | ACHEMAPTTSHRNPSR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0980350-A4 | HYDROXYNAPHTHOIC ACIDS AND DERIVATIVES | UNIV NEW MEXICO (US) | 2003-01-02 | — | — | EP | disclosed |
| US-6124498-A | Hydroxynaphthoic acids and derivatives | UNIVERSITY OF NEW MEXICO (US) | 2000-09-26 | — | — | US | disclosed |
| EP-0980350-A2 | HYDROXYNAPHTHOIC ACIDS AND DERIVATIVES | The University of New Mexico (US) | 2000-02-23 | — | — | EP | disclosed |
| WO-1998049130-A2 | HYDROXYNAPHTHOIC ACIDS AND DERIVATIVES | THE UNIVERSITY OF NEW MEXICO (US) | 1998-11-05 | — | — | WO | disclosed |