Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.41 |
| ▸ | CES1 | P23141 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | GLA | P06280 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | IAPP | P10997 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7195797 | 0.90 | CES2 (0.44) | CES2CES1L3MBTL1TP53ALDH1A1 | |
| SCHEMBL7190978 | 0.89 | CES2 (0.45) | CES2CES1TP53LMNAMAPT | |
| SCHEMBL7184125 | 0.85 | CES2 (0.40) | CES2CES1L3MBTL1SMN1; SMN2HPGD | |
| SCHEMBL7190329 | 0.82 | DUT (0.43) | CES2CES1L3MBTL1SMN1; SMN2HPGD | |
| SCHEMBL8199953 | 0.81 | CES2 (0.37) | CES2CES1L3MBTL1SMN1; SMN2HPGD | |
| SCHEMBL7195643 | 0.76 | DUT (0.39) | CES2CES1L3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL7190867 | 0.76 | CES2 (0.42) | CES2CES1L3MBTL1TP53LMNA | |
| SCHEMBL7190720 | 0.74 | DUT (0.43) | ALOX5LMNAMAPTALDH1A1GAA | |
| SCHEMBL7188133 | 0.73 | DUT (0.43) | CES2CES1L3MBTL1SMN1; SMN2HPGD | |
| SCHEMBL7185042 | 0.72 | DUT (0.43) | CES2CES1SMN1; SMN2TP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6534665-B1 | Used for polymerization and copolymerization of olefins | REPSOL QUIMICA S.A. (ES) | 2003-03-18 | — | — | US | claimed |
| US-6534665-B1 | Used for polymerization and copolymerization of olefins | REPSOL QUIMICA S.A. (ES) | 2003-03-18 | — | — | US | disclosed |