Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 3/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.37 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7189972 | 0.90 | MAPT (0.44) | ERN1GSTP1ALDH1A1CYP2A6TTR | |
| SCHEMBL7190071 | 0.87 | GSTP1 (0.39) | ERN1GSTP1ALDH1A1CYP2A6TTR | |
| SCHEMBL7200140 | 0.87 | ESR1 (0.49) | ESR1ESR2ALDH1A1 | |
| SCHEMBL7200144 | 0.87 | ESR1 (0.49) | ESR1ESR2ALDH1A1 | |
| SCHEMBL7191254 | 0.87 | ESR1 (0.44) | GSTP1ESR1ESR2ALDH1A1CYP2A6 | |
| SCHEMBL7189743 | 0.86 | ALDH1A1 (0.49) | GSTP1ESR1ESR2ALDH1A1CYP2A6 | |
| SCHEMBL7928746 | 0.86 | DHFR (0.41) | TRPA1GSTP1ESR1ESR2ALDH1A1 | |
| SCHEMBL1359561 | 0.84 | ESR1 (0.47) | GSTP1ESR1ESR2ALDH1A1CYP2A6 | |
| SCHEMBL7940195 | 0.83 | HSPB1 (0.46) | TRPA1GSTP1ESR1ESR2PTGS2 | |
| SCHEMBL6050146 | 0.83 | GSTP1 (0.43) | ERN1GSTP1ESR1ESR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0835867-B1 | 1-Aryloxy-2-arylnaphthyl compounds, intermediates, compositions, and methods | LILLY CO ELI (US) | 2003-12-03 | — | — | EP | disclosed |
| US-5916916-A | USEFUL AS SELECTIVE ESTROGEN RECEPTOR MODULATORS. | ELI LILLY AND COMPANY (US) | 1999-06-29 | — | — | US | disclosed |
| EP-0835867-A1 | 1-Aryloxy-2-arylnaphthyl compounds, intermediates, compositions, and methods | ELI LILLY AND COMPANY (US) | 1998-04-15 | — | — | EP | disclosed |