SCHEMBL7194801

SCHEMBL7194801

Cc1c(C[O])cccc1-c1ccccc1

nearest known ligand 0.69

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CD274 Q9NZQ7 14/20 0.69
PDCD1 Q15116 3/20 0.69
DPP4 P27487 1/20 0.45
PTGS1 P23219 1/20 0.45
EPHX1 P07099 2/20 0.44
KMT2A Q03164 1/20 0.43
FOLH1 Q04609 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL607544 0.86 CD274 (0.71) CD274PDCD1DPP4PTGS1EPHX1
SCHEMBL358303 0.82 CD274 (1.00) CD274PDCD1DPP4PTGS1EPHX1
SCHEMBL29558512 0.82 CD274 (1.00) CD274PDCD1DPP4PTGS1EPHX1
SCHEMBL155695 0.81 DPP4 (0.60) CD274PDCD1DPP4KMT2AFOLH1
SCHEMBL4151221 0.80 CD274 (0.69) CD274PDCD1DPP4PTGS1EPHX1
SCHEMBL30084702 0.80 CD274 (0.69) CD274PDCD1DPP4PTGS1EPHX1
SCHEMBL3793203 0.80 CD274 (0.69) CD274PDCD1DPP4PTGS1EPHX1
SCHEMBL7107915 0.80 CD274 (0.69) CD274PDCD1DPP4PTGS1EPHX1
SCHEMBL21153739 0.80 CD274 (0.69) CD274PDCD1DPP4PTGS1EPHX1
SCHEMBL1515737 0.79 CD274 (0.62) CD274PDCD1DPP4PTGS1EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003053905-A1 A PROCESS FOR THE PRODUCTION OF 1R PYRETHROID ESTERS SYNGENTA LIMITED (GB) 2003-07-03 WO claimed