SCHEMBL7195072

SCHEMBL7195072

N=Cc1ccc(O)c2ccccc12

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 6/20 0.59
EP300 Q09472 2/20 0.46
KAT2B Q92831 2/20 0.46
KAT8 Q9H7Z6 2/20 0.46
HDAC3 O15379 1/20 0.46
NCOR2 Q9Y618 1/20 0.46
CTSL P07711 4/20 0.46
CAPN1 P07384 3/20 0.46
CTSB P07858 3/20 0.46
GCGR P47871 3/20 0.41
LDHA P00338 1/20 0.41
CYP1A2 P05177 1/20 0.39
APP P05067 1/20 0.39
MAPT P10636 1/20 0.39
THRB P10828 1/20 0.39
HPGD P15428 1/20 0.39
ALOX15 P16050 1/20 0.39
TSHR P16473 1/20 0.39
CASP1 P29466 1/20 0.39
SNCA P37840 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7708552 0.81 IDO1 (0.65) IDO1EP300KAT2BKAT8HDAC3
SCHEMBL146732 0.77 IDO1 (0.59) IDO1EP300KAT2BKAT8HDAC3
SCHEMBL29673385 0.77 IDO1 (0.59) IDO1EP300KAT2BKAT8HDAC3
SCHEMBL501996 0.77 IDO1 (0.59) IDO1EP300KAT2BKAT8HDAC3
SCHEMBL29638 0.77 IDO1 (1.00) IDO1EP300KAT2BKAT8HDAC3
SCHEMBL29362983 0.77 IDO1 (1.00) IDO1EP300KAT2BKAT8HDAC3
SCHEMBL32677325 0.77 IDO1 (1.00) IDO1EP300KAT2BKAT8HDAC3
SCHEMBL17548944 0.74 IDO1 (0.54) IDO1EP300KAT2BKAT8HDAC3
SCHEMBL17988288 0.74 IDO1 (0.54) IDO1EP300KAT2BKAT8HDAC3
SCHEMBL21010599 0.74 LMNA (0.50) IDO1EP300MAPTTHRBRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1441637-A Compositions for repelling crawling insects BAYER AG (DE) 2003-09-10 CN disclosed
EP-1304924-A2 COMPOSITIONS FOR REPELLING CRAWLING INSECTS Bayer Aktiengesellschaft (DE) 2003-05-02 EP disclosed
US-20020094993-A1 Compositions for repelling crawling insects S.C. JOHNSON & SON, INC. 2002-07-18 US disclosed
WO-2002005646-A2 COMPOSITIONS FOR REPELLING CRAWLING INSECTS S.C. JOHNSON & SON, INC. (US) (US) 2002-01-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020094993-A1 Compositions for repelling crawling insects ACHE, DDT, GAP43 IDO1 2046/4885EP300 756/4885KAT2B 536/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.