Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | ERN1 | O75460 | 6/20 | 0.56 |
| ▸ | TLR2 | O60603 | 1/20 | 0.56 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.56 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | PIM1 | P11309 | 1/20 | 0.48 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CFTR | P13569 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5198420 | 0.84 | KDM4E (0.57) | KDM4EL3MBTL1LMNATSHRALDH1A1 | |
| SCHEMBL121356 | 0.83 | LMNA (0.57) | KDM4ELMNATSHRALDH1A1POLB | |
| SCHEMBL30635255 | 0.83 | LMNA (0.57) | KDM4ELMNATSHRALDH1A1POLB | |
| SCHEMBL1538293 | 0.82 | TSHR (0.65) | KDM4EL3MBTL1LMNATSHRALDH1A1 | |
| SCHEMBL16566856 | 0.82 | ALDH1A1 (0.59) | KDM4EL3MBTL1ERN1TLR2TLR1 | |
| SCHEMBL26617428 | 0.82 | CA1 (0.50) | KDM4EL3MBTL1ERN1TLR2TLR1 | |
| SCHEMBL31184600 | 0.82 | ALDH1A1 (0.59) | KDM4EL3MBTL1ERN1TLR2TLR1 | |
| SCHEMBL29216778 | 0.82 | ALDH1A1 (0.49) | KDM4EL3MBTL1ERN1TLR2TLR1 | |
| Benzene SCHEMBL28217563 | 0.81 | TSHR (0.55) | KDM4ELMNATSHRALDH1A1POLB | |
| SCHEMBL1092958 | 0.81 | CA1 (0.50) | KDM4EL3MBTL1ERN1TLR2TLR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-1246273-A | — | — | None | — | — | JP | disclosed |
| CN-108602811-B | FXR receptor agonists | 轩竹生物科技有限公司 | 2021-11-16 | — | — | CN | disclosed |
| EP-3212647-B1 | NOVEL PYRIDOPYRIMIDINONE COMPOUNDS FOR MODULATING THE CATALYTIC ACTIVITY OF HISTONE LYSINE DEMETHYLASES (KDMS) | DONG A ST CO LTD (KR) | 2019-04-03 | — | — | EP | disclosed |
| EP-3212647-B1 | NOVEL PYRIDOPYRIMIDINONE COMPOUNDS FOR MODULATING THE CATALYTIC ACTIVITY OF HISTONE LYSINE DEMETHYLASES (KDMS) | DONG A ST CO LTD (KR) | 2019-04-03 | — | — | EP | disclosed |
| EP-2928879-B1 | PHENYLETHYLPYRIDINE DERIVATIVES AS PDE4-INHIBITORS AND MUSCARINIC RECEPTOR ANTAGONISTS | CHIESI FARM SPA (IT) | 2018-02-28 | — | — | EP | disclosed |
| EP-2928880-B1 | PHENYLETHYLPYRIDINE DERIVATIVES AS PDE4-INHIBITORS AND MUSCARINIC RECEPTOR ANTAGONISTS | CHIESI FARM SPA (IT) | 2018-02-14 | — | — | EP | disclosed |
| US-9890151-B2 | 3,5-dichloro,4-(3,4-(cyclo-)alkoxyphenyl)- 2-carbonyloxy)ethyl)pyridine derivatives as PDE-4 inhibitors | CHIESI FARMACEUTICI S.P.A. (IT) | 2018-02-13 | — | — | US | disclosed |
| US-9834550-B2 | Pyridopyrimidinone compounds for modulating the catalytic activity of histone lysine demethylases (KDMs) | DONG-A ST CO., LTD. (KR) | 2017-12-05 | — | — | US | disclosed |
| US-9834550-B2 | Pyridopyrimidinone compounds for modulating the catalytic activity of histone lysine demethylases (KDMs) | DONG-A ST CO., LTD. (KR) | 2017-12-05 | — | — | US | disclosed |
| US-9834550-B2 | Pyridopyrimidinone compounds for modulating the catalytic activity of histone lysine demethylases (KDMs) | DONG-A ST CO., LTD. (KR) | 2017-12-05 | — | — | US | disclosed |
| US-20140155427-A1 | NOVEL COMPOUNDS | CHIESI FARMACEUTICI S.P.A. (IT) | 2014-06-05 | — | — | US | disclosed |
| US-20140155428-A1 | NOVEL COMPOUNDS | CHIESI FARMACEUTICI S.P.A (IT) | 2014-06-05 | — | — | US | disclosed |
| US-6593315-B2 | For controlling phytopathogenic harmful fungi | BASF AKTIENGESELLSCHAFT (DE) | 2003-07-15 | — | — | US | disclosed |
| US-20020032178-A1 | Salicylic acid derivatives, processes for their preparation, compositions comprising them, their use | BASF AKTIENGESELLSCHAFT (DE) | 2002-03-14 | — | — | US | disclosed |
| US-4882340-A | INHIBITS REFLECTIVE CONTRACTION OF URINARY BLADDER | TANABE SEIYAKU CO., LTD. (JP) | 1989-11-21 | — | — | US | disclosed |
| JP-H01246273-A | DIHYDROBENZOFURANONE DERIVATIVE | KISSEI PHARMACEUT CO LTD | 1989-10-02 | — | — | JP | disclosed |
| US-4829067-A | INHIBITORS OF REFLECTIVE CONTRACTION OF BLADDER | TANABE SEIYAKU CO., LTD. (JP) | 1989-05-09 | — | — | US | disclosed |
| CN-1031840-A | Benzofuran derivative and preparation method thereof | TANABE SEIYAKU CO (JP) | 1989-03-22 | — | — | CN | disclosed |
| EP-0306226-A2 | A benzofuran derivative and processes for preparing the same | Tanabe Seiyaku Co., Ltd. (JP) | 1989-03-08 | — | — | EP | disclosed |
| EP-0270342-A2 | A benzo-furan (or -thiophene) derivative and processes for preparing the same | Tanabe Seiyaku Co., Ltd. (JP) | 1988-06-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140155427-A1 | NOVEL COMPOUNDS | CHRM3, PDE4A, PDE3A | KDM4E 2743/4885L3MBTL1 2711/4885ERN1 2238/4885 |
| US-20140155428-A1 | NOVEL COMPOUNDS | PDE4A, CHRM3, PDE4B | KDM4E 2661/4885L3MBTL1 2741/4885ERN1 2145/4885 |
| US-20020032178-A1 | Salicylic acid derivatives, processes for their preparation, compositions comprising them, their use | NOD1, HAO1, HAAO | KDM4E 3550/4885L3MBTL1 4244/4885ERN1 1379/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.