Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31299896 | 0.85 | PIN1 (0.58) | ALDH1A1HPGDHSD17B10KDM4EHTT | |
| SCHEMBL10171847 | 0.85 | PIN1 (0.58) | ALDH1A1HPGDHSD17B10KDM4EHTT | |
| SCHEMBL28047070 | 0.81 | ALDH1A1 (0.48) | ALDH1A1HPGDHSD17B10KDM4ELMNA | |
| SCHEMBL18416022 | 0.80 | KDM4E (0.60) | ALDH1A1HPGDHSD17B10KDM4ETSHR | |
| SCHEMBL3376213 | 0.79 | ALDH1A1 (0.57) | ALDH1A1HPGDHSD17B10KDM4ELMNA | |
| SCHEMBL13657349 | 0.79 | ALDH1A1 (0.57) | ALDH1A1HPGDHSD17B10KDM4ELMNA | |
| SCHEMBL17321065 | 0.79 | ALDH1A1 (0.42) | ALDH1A1HPGDHSD17B10KDM4ELMNA | |
| SCHEMBL17324090 | 0.79 | TSHR (0.47) | ALDH1A1HPGDHSD17B10KDM4ELMNA | |
| SCHEMBL4130899 | 0.78 | ALDH1A1 (1.00) | ALDH1A1HPGDHSD17B10KDM4ELMNA | |
| SCHEMBL4454971 | 0.75 | ALDH1A1 (0.47) | ALDH1A1KDM4ETSHRSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10907197-B2 | Probes for imaging huntingtin protein | CHDI FOUNDATION, INC. (US) | 2021-02-02 | — | — | US | disclosed |
| US-10907197-B2 | Probes for imaging huntingtin protein | CHDI FOUNDATION, INC. (US) | 2021-02-02 | — | — | US | disclosed |
| EP-3190888-B1 | PROBES FOR IMAGING HUNTINGTIN PROTEIN | CHDI FOUNDATION INC (US) | 2020-06-10 | — | — | EP | disclosed |
| EP-3124478-B1 | NOVEL ORGANOLEPTIC COMPOUNDS | INT FLAVORS & FRAGRANCES INC (US) | 2018-10-31 | — | — | EP | disclosed |
| US-9816048-B2 | Organoleptic compounds | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2017-11-14 | — | — | US | disclosed |
| US-9816048-B2 | Organoleptic compounds | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2017-11-14 | — | — | US | disclosed |
| US-9816048-B2 | Organoleptic compounds | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2017-11-14 | — | — | US | disclosed |
| CN-105164112-B | Amide compound and preparation method, pharmaceutical composition and application thereof | 中国科学院上海药物研究所 | 2017-10-13 | — | — | CN | disclosed |
| US-20170292150-A1 | PROBES FOR IMAGING HUNTINGTIN PROTEIN | CHDI FOUNDATION, INC. | 2017-10-12 | — | — | US | disclosed |
| US-20170292150-A1 | PROBES FOR IMAGING HUNTINGTIN PROTEIN | CHDI FOUNDATION, INC. | 2017-10-12 | — | — | US | disclosed |
| US-9212336-B2 | 3-methyl-benzofuran-5-ol and its use in perfume compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2015-12-15 | — | — | US | disclosed |
| US-9212336-B2 | 3-methyl-benzofuran-5-ol and its use in perfume compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2015-12-15 | — | — | US | disclosed |
| US-20150111810-A1 | 3-METHYL-BENZOFURAN-5-OL AND ITS USE IN PERFUME COMPOSITIONS | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2015-04-23 | — | — | US | disclosed |
| US-20150111810-A1 | 3-METHYL-BENZOFURAN-5-OL AND ITS USE IN PERFUME COMPOSITIONS | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2015-04-23 | — | — | US | disclosed |
| US-20150111810-A1 | 3-METHYL-BENZOFURAN-5-OL AND ITS USE IN PERFUME COMPOSITIONS | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2015-04-23 | — | — | US | disclosed |
| EP-2862918-A1 | 3-methyl-benzofuran-5-ol and its use in perfume compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2015-04-22 | — | — | EP | disclosed |
| US-8436043-B2 | Heterocyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-05-07 | — | — | US | disclosed |
| US-20120270865-A2 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-10-25 | — | — | US | disclosed |
| US-20120053173-A1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-01 | — | — | US | disclosed |
| EP-2251326-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2010-11-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120053173-A1 | HETEROCYCLIC COMPOUND | SLC5A2, SLC5A1, IAPP | ALDH1A1 504/4885HPGD 486/4885HSD17B10 691/4885 |
| US-20120270865-A2 | HETEROCYCLIC COMPOUND | SLC5A2, SLC5A1, IAPP | ALDH1A1 504/4885HPGD 486/4885HSD17B10 691/4885 |
| US-10907197-B2 | Probes for imaging huntingtin protein | HTT, HYPK, FABP7 | ALDH1A1 3949/4885HPGD 2117/4885HSD17B10 883/4885 |
| US-20170292150-A1 | PROBES FOR IMAGING HUNTINGTIN PROTEIN | HTT, HYPK, FABP7 | ALDH1A1 3949/4885HPGD 2117/4885HSD17B10 883/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.