Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 3/20 | 0.49 |
| ▸ | MAOB | P27338 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9057896 | 0.86 | ALDH1A1 (0.60) | ALDH1A1LMNATSHRHTTRAB9A | |
| SCHEMBL23287848 | 0.85 | PIN1 (0.57) | ALDH1A1RAB9AKMT2ASMN1; SMN2HPGD | |
| SCHEMBL719569 | 0.79 | ALDH1A1 (0.63) | ALDH1A1LMNATSHRHTTRAB9A | |
| SCHEMBL13657349 | 0.78 | ALDH1A1 (0.57) | ALDH1A1LMNATSHRHTTRAB9A | |
| SCHEMBL5242625 | 0.76 | RAB9A (0.61) | ALDH1A1LMNARAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL6217970 | 0.75 | MTNR1A (0.64) | ALDH1A1LMNATSHRHTTMTNR1A | |
| SCHEMBL28006934 | 0.74 | PTPN1 (0.53) | ALDH1A1TSHRHTTRAB9AKMT2A | |
| SCHEMBL30695267 | 0.74 | PTPN1 (0.53) | ALDH1A1TSHRHTTRAB9AKMT2A | |
| SCHEMBL17237762 | 0.74 | ALDH1A1 (0.62) | ALDH1A1LMNATSHRHTTRAB9A | |
| SCHEMBL30963763 | 0.74 | ALDH1A1 (0.62) | ALDH1A1LMNATSHRHTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4048675-A1 | COMPOUNDS THAT CAN BE USED IN AN ORGANIC ELECTRONIC DEVICE | Merck Patent GmbH (DE) | 2022-08-31 | — | — | EP | disclosed |
| CN-114630831-A | Compounds useful in organic electronic devices | 默克专利有限公司 | 2022-06-14 | — | — | CN | disclosed |
| WO-2021078831-A1 | COMPOUNDS THAT CAN BE USED IN AN ORGANIC ELECTRONIC DEVICE | MERCK PATENT GMBH (DE) | 2021-04-29 | — | — | WO | disclosed |
| EP-1653944-B1 | HETEROCYCLIC COMPOUNDS USEFUL AS MALONYL-COA DECARBOXYLASE INHIBITORS | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2010-11-10 | — | — | EP | disclosed |
| EP-1653944-B1 | HETEROCYCLIC COMPOUNDS USEFUL AS MALONYL-COA DECARBOXYLASE INHIBITORS | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2010-11-10 | — | — | EP | disclosed |
| US-7696365-B2 | Heterocyclic compounds useful as malonyl-CoA decarboxylase inhibitors | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2010-04-13 | — | — | US | disclosed |
| US-7696365-B2 | Heterocyclic compounds useful as malonyl-CoA decarboxylase inhibitors | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2010-04-13 | — | — | US | disclosed |
| US-7696365-B2 | Heterocyclic compounds useful as malonyl-CoA decarboxylase inhibitors | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2010-04-13 | — | — | US | disclosed |
| WO-2010016552-A1 | THERAPEUTIC AGENT FOR IRRITABLE BOWEL SYNDROME | 武田薬品工業株式会社 (JP) | 2010-02-11 | — | — | WO | disclosed |
| EP-1653944-A1 | HETEROCYCLIC COMPOUNDS USEFUL AS MALONYL-COA DECARBOXYLASE INHIBITORS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2006-05-10 | — | — | EP | disclosed |
| US-20060058295-A1 | Novel compounds as pharmaceutical agents | ELI LILLY AND COMPANY (US) | 2006-03-16 | — | — | US | disclosed |
| WO-2005011670-A1 | HETEROCYCLIC COMPOUNDS USEFUL AS MALONYL-COA DECARBOXYLASE INHIBITORS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2005-02-10 | — | — | WO | disclosed |
| WO-2005011670-A1 | HETEROCYCLIC COMPOUNDS USEFUL AS MALONYL-COA DECARBOXYLASE INHIBITORS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2005-02-10 | — | — | WO | disclosed |
| US-20050026969-A1 | Heterocyclic compounds useful as malonyl-CoA decarboxylase inhibitors | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2005-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060058295-A1 | Novel compounds as pharmaceutical agents | TGFB1, TGFB2, TGFBR1 | ALDH1A1 1346/4885LMNA 2799/4885TSHR 1511/4885 |
| US-20050026969-A1 | Heterocyclic compounds useful as malonyl-CoA decarboxylase inhibitors | ACACA, ACACB, PC | ALDH1A1 270/4885LMNA 3573/4885TSHR 4509/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.