Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.36 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 6/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6920283 | 0.80 | FFAR4 (0.41) | MAPK1KMT2AMEN1GAASMN1; SMN2 | |
| SCHEMBL7196034 | 0.76 | MRGPRX4 (0.41) | MAPK1KMT2AMEN1POLB | |
| SCHEMBL7192436 | 0.75 | CYP1A2 (0.34) | MAPK1KMT2AMEN1SMN1; SMN2CYP1A2 | |
| SCHEMBL7196713 | 0.73 | PPARG (0.44) | SMN1; SMN2LMNAALOX5AP | |
| SCHEMBL7191526 | 0.71 | ALDH1A1 (0.35) | KMT2AMEN1GAASMN1; SMN2CYP1A2 | |
| SCHEMBL6922932 | 0.67 | MAPK1 (0.41) | MAPK1KMT2AMEN1GAASMN1; SMN2 | |
| SCHEMBL7193404 | 0.65 | ALOX5AP (0.35) | SMN1; SMN2LMNAALOX5AP | |
| SCHEMBL6490952 | 0.63 | ALOX5AP (0.43) | KMT2AMEN1GAASMN1; SMN2ALOX5AP | |
| SCHEMBL7196484 | 0.63 | DCTPP1 (0.34) | ALOX5AP | |
| SCHEMBL9335318 | 0.62 | MEN1 (0.38) | MAPK1KMT2AMEN1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004108686-A2 | BENZIMIDAZOLE COMPOUNDS HAVING HYPOGLYCEMIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-12-16 | — | — | WO | disclosed |