Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP4Z1 | Q86W10 | 4/20 | 0.35 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.35 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | G6PD | P11413 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28910359 | 0.75 | EPHX1 (0.48) | CYP1A2S1PR2S1PR1S1PR3EPHX1 | |
| SCHEMBL25430771 | 0.72 | GPR84 (0.44) | — | |
| SCHEMBL28737767 | 0.70 | GPR84 (0.38) | CYP1A2CYP4Z1ASAH1EPHX1 | |
| SCHEMBL9763767 | 0.70 | CRBN (0.42) | — | |
| SCHEMBL19628813 | 0.67 | CYP4Z1 (0.42) | CYP4Z1ASAH1EPHX1ALDH1A1NAAA | |
| SCHEMBL1465952 | 0.65 | CYP4Z1 (0.47) | CYP4Z1ASAH1 | |
| SCHEMBL27903571 | 0.64 | MGLL (0.57) | CYP4Z1ASAH1EPHX1ALDH1A1TP53 | |
| SCHEMBL27921301 | 0.64 | MGLL (0.57) | CYP4Z1ASAH1EPHX1ALDH1A1TP53 | |
| SCHEMBL20360089 | 0.64 | MGLL (0.57) | CYP4Z1ASAH1EPHX1ALDH1A1TP53 | |
| SCHEMBL28035741 | 0.64 | MGLL (0.57) | CYP4Z1ASAH1EPHX1ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1318168-A1 | Stabiliser combinations for chlorinated polymers | Crompton Vinyl Additives GmbH (DE) | 2003-06-11 | — | — | EP | disclosed |