SCHEMBL9763767

SCHEMBL9763767

CCCCCNn1ccc(=O)[nH]c1=O

nearest known ligand 0.57

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 2/20 0.42
GPR84 Q9NQS5 9/20 0.41
PKM P14618 1/20 0.39
DUT P33316 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25430771 0.98 GPR84 (0.44) CRBNGPR84
SCHEMBL8933242 0.78 CRBN (0.41) CRBNPKMDUT
SCHEMBL7837324 0.71 DUT (0.56) CRBNPKMDUT
SCHEMBL3541014 0.71 CRBN (0.54) CRBNPKMDUT
SCHEMBL3752207 0.70 CRBN (0.40) CRBNPKMDUT
SCHEMBL17372138 0.70 DUT (0.55) PKMDUT
SCHEMBL6268140 0.70 CRBN (0.42) CRBNGPR84DUT
SCHEMBL7196314 0.70 CYP1A2 (0.36)
SCHEMBL6864606 0.69 DUT (0.57) CRBNPKMDUT
SCHEMBL7926412 0.69 PKM (0.40) CRBNPKMDUT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114369067-A Acylamino uracil and preparation method and application thereof 广东科力新材料有限公司 2022-04-19 CN claimed
JP-3215475-A None JP disclosed
CN-114369067-A Acylamino uracil and preparation method and application thereof 广东科力新材料有限公司 2022-04-19 CN disclosed
CN-114369067-A Acylamino uracil and preparation method and application thereof 广东科力新材料有限公司 2022-04-19 CN disclosed
CN-114369067-A Acylamino uracil and preparation method and application thereof 广东科力新材料有限公司 2022-04-19 CN disclosed
JP-H03215475-A PRODUCTION OF 1-AMINO-5-HALOGENOURACIL YAMASA SHOYU CO LTD 1991-09-20 JP disclosed