Diphenylmethane

Diphenylmethane

SCHEMBL719634

O=c1o[nH]c2ccccc12.c1ccc(Cc2ccccc2)cc1

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 3/20 0.46
▸ MEN1 O00255 2/20 0.46
▸ ELANE P08246 2/20 0.46
▸ KDM4E B2RXH2 3/20 0.44
▸ ALDH1A1 P00352 3/20 0.44
▸ CALM1 P0DP23 1/20 0.43
▸ F2 P00734 1/20 0.42
▸ CFD P00746 1/20 0.42
▸ NQO1 P15559 1/20 0.41
▸ PARP1 P09874 1/20 0.40
▸ AR P10275 1/20 0.40
▸ HPGD P15428 2/20 0.39
▸ SMN1; SMN2 Q16637 1/20 0.39
▸ GPR55 Q9Y2T6 1/20 0.39
▸ GAA P10253 1/20 0.38
▸ HTT P42858 1/20 0.38
▸ HSD17B10 Q99714 1/20 0.38
▸ CTRC Q99895 1/20 0.38
▸ CYP1A2 P05177 1/20 0.37
▸ CYP3A4 P08684 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL158747 0.87 F2 (0.52) KMT2AMEN1KDM4EALDH1A1F2
SCHEMBL29440558 0.87 F2 (0.52) KMT2AMEN1KDM4EALDH1A1F2
Methane SCHEMBL29008285 0.85 F2 (0.50) KMT2AMEN1KDM4EALDH1A1F2
SCHEMBL27917107 0.75 KDM4E (0.52) KMT2AMEN1KDM4EALDH1A1F2
2-Phenyl-1H-Indole SCHEMBL28384256 0.70 NPC1 (0.63) KMT2AMEN1KDM4EALDH1A1HPGD
SCHEMBL1673185 0.66 DAO (0.61) KMT2AMEN1ELANEKDM4EALDH1A1
Diphenylmethane SCHEMBL3792579 0.66 CALM1 (1.00) KDM4EALDH1A1CALM1HPGDHSD17B10
Diphenylmethane SCHEMBL4361124 0.66 CALM1 (1.00) KDM4EALDH1A1CALM1HPGDHSD17B10
Diphenylmethane SCHEMBL1303 0.66 CALM1 (1.00) KDM4EALDH1A1CALM1HPGDHSD17B10
Diphenylmethane SCHEMBL14763944 0.66 CALM1 (1.00) KDM4EALDH1A1CALM1HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 388 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2431444-B1 THERMOCHROMIC COLOR-MEMORY COMPOSITION, AND THERMOCHROMIC COLOR-MEMORY MICROCAPSULE PIGMENT HAVING THE COMPOSITION ENCAPSULATED THEREIN PILOT INK CO LTD (JP) 2019-11-13 — — EP claimed
EP-2873708-B1 Adhesive composition ARTIMELT AG (CH) 2019-02-13 — — EP claimed
US-9939747-B2 Developing agent and method for producing the same TOSHIBA TEC KABUSHIKI KAISHA (JP) 2018-04-10 — — US claimed
US-9644117-B2 Adhesive composition ARTIMELT AG (CH) 2017-05-09 — — US claimed
US-20170038698-A1 DEVELOPING AGENT AND METHOD FOR PRODUCING THE SAME TOSHIBA TEC KABUSHIKI KAISHA (JP) 2017-02-09 — — US claimed
US-20160289508-A1 ADHESIVE COMPOSITION ARTIMELT AG (CH) 2016-10-06 — — US claimed
WO-2015074953-A1 ADHESIVE COMPOSITION COLLANO ADHESIVES AG (CH) 2015-05-28 — — WO claimed
EP-2873708-A1 Adhesive composition Collano Adhesives AG (CH) 2015-05-20 — — EP claimed
EP-2809733-A1 THERMOCHROMIC SYSTEMS WITH CONTROLLED HYSTERESIS Chromatic Technologies, Inc. (US) 2014-12-10 — — EP claimed
WO-2013115800-A1 THERMOCHROMIC SYSTEMS WITH CONTROLLED HYSTERESIS CHROMATIC TECHNOLOGIES, INC. (US) 2013-08-08 — — WO claimed
US-20130193386-A1 THERMOCHROMIC SYSTEMS WITH CONTROLLED HYSTERESIS CHROMATIC TECHNOLOGIES, INC. 2013-08-01 — — US claimed
US-12043596-B2 Thermochromic pigment compositions SOCIETE BIC (FR) 2024-07-23 — — US disclosed
CN-118369124-A Composition for wetness indicator and wetness indicator 汉高股份有限及两合公司 2024-07-19 — — CN disclosed
CN-118339237-A Reversible thermochromic microcapsule pigments 株式会社百乐 2024-07-12 — — CN disclosed
US-12011943-B2 Image forming apparatus TOSHIBA TEC KABUSHIKI KAISHA (JP) 2024-06-18 — — US disclosed
US-5721059-A THERMOCHROMIC BLENDS COMPRISING AN ELECTRON-DONATING COLOR DYES, A PHENOLIC HYDROXY RADICAL AND A COMPOUND SELECTED FROM ALCOHOLS, ESTERS, KETONES AND CARBOXYLIC ACIDS IN VINYL ACETATE-VINYL CHLORIDE COPOLYMER; TOYS, COMPUTERS, OPTICS THE PILOT INK CO., LTD. (JP) 1998-02-24 — — US disclosed
US-5585425-A Thermochromic opaque/transparent composition, laminate member employing the same, and three-dimensional member employing said laminate member and capable of concealing and revealing the interior THE PILOT INK CO., LTD. (JP) 1996-12-17 — — US disclosed
US-5490956-A Thermochromic opaque composition, laminate member employing the same, and three-dimensional member employing said laminate member and capable of concealing and revealing the interior PILOT INK CO., LTD. (JP) 1996-02-13 — — US disclosed
EP-0677564-A2 Opaque/transparent thermochromic compositions and laminate THE PILOT INK CO., LTD. (JP) 1995-10-18 — — EP disclosed
EP-0595577-A2 Thermochromic opaque composition and uses thereof THE PILOT INK CO., LTD. (JP) 1994-05-04 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12043596-B2 Thermochromic pigment compositions TYR, MITF, CRY2 KMT2A 1061/4885MEN1 1133/4885ELANE 4677/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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