SCHEMBL7196430

SCHEMBL7196430

CCC1(OC(=O)c2ccc(C(=O)OC3(CC)CCCCC3)cc2)CCCCC1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.41
NPSR1 Q6W5P4 3/20 0.41
CYP1A2 P05177 2/20 0.41
CYP3A4 P08684 2/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
GAA P10253 1/20 0.39
LMNA P02545 4/20 0.39
RAB9A P51151 4/20 0.39
NPC1 O15118 3/20 0.39
HTT P42858 2/20 0.39
ALDH1A1 P00352 3/20 0.39
TDP1 Q9NUW8 2/20 0.39
ESR1 P03372 2/20 0.38
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24306003 0.94 TDP1 (0.44) SMN1; SMN2NPSR1CYP1A2CYP3A4MEN1
SCHEMBL9618428 0.92 LMNA (0.45) SMN1; SMN2NPSR1CYP1A2CYP3A4MEN1
SCHEMBL3671321 0.90 LMNA (0.46) SMN1; SMN2NPSR1CYP1A2CYP3A4MEN1
SCHEMBL25779631 0.89 SMN1; SMN2 (0.37) SMN1; SMN2NPSR1CYP1A2CYP3A4MEN1
SCHEMBL23817401 0.88 TSHR (0.42) CYP1A2CYP3A4MEN1KMT2ACYP2C19
SCHEMBL24948256 0.88 TAS1R3 (0.39) SMN1; SMN2NPSR1CYP1A2CYP3A4MEN1
SCHEMBL12040206 0.87 TSHR (0.40) SMN1; SMN2NPSR1CYP1A2CYP3A4MEN1
SCHEMBL22263821 0.87 SMN1; SMN2 (0.35) SMN1; SMN2NPSR1CYP1A2CYP3A4MEN1
SCHEMBL23817403 0.86 CES2 (0.42) CYP1A2CYP3A4MEN1KMT2ACYP2C19
SCHEMBL9963791 0.86 TAS1R3 (0.40) SMN1; SMN2NPSR1CYP1A2CYP3A4MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-5140424-A None JP disclosed
JP-4110344-A None JP disclosed
CN-105209941-A Resin molding material for light reflector, and lighting fixture PANASONIC IP MAN CO LTD 2015-12-30 CN disclosed
EP-0838484-B1 FUNCTIONAL BLOCK COPOLYMER AND PROCESS FOR PREPARING THE SAME TAKIRON CO (JP) 2003-10-08 EP disclosed
US-6359081-B1 FOR COMPATIBILIZING TAKIRON CO., LTD. (JP) 2002-03-19 US disclosed
EP-0838484-A1 FUNCTIONAL BLOCK COPOLYMER AND PROCESS FOR PREPARING THE SAME TAKIRON CO. LTD. (JP) 1998-04-29 EP disclosed
EP-0605194-A2 Transparent polycarbonate-polyester-blends GE PLASTICS JAPAN LIMITED (JP) 1994-07-06 EP disclosed
JP-H05140424-A HIGH-IMPACT POLYESTER RESIN COMPOSITION NIPPON G II PLAST KK 1993-06-08 JP disclosed
JP-H04110344-A IMPACT-RESISTANT POLYESTER RESIN COMPOSITION NIPPON G II PLAST KK 1992-04-10 JP disclosed
US-3996000-A USING THE EXHAUSTION PROCESS BAYER AKTIENGESELLSCHAFT (DT) 1976-12-07 US disclosed