Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WEE1 | P30291 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PRKCI | P41743 | 6/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7199532 | 0.83 | KDM4E (0.58) | WEE1KDM4ERXFP1ALDH1A1MAPT | |
| SCHEMBL7195650 | 0.81 | PRKCI (0.47) | WEE1KDM4EALDH1A1MAPTLMNA | |
| SCHEMBL969839 | 0.80 | KDM4E (0.58) | WEE1KDM4ERXFP1ALDH1A1MAPT | |
| SCHEMBL7199531 | 0.78 | RXFP1 (0.52) | WEE1KDM4ERXFP1ALDH1A1MAPT | |
| SCHEMBL7172235 | 0.77 | KDM4E (0.56) | KDM4EALDH1A1MAPTLMNAHTT | |
| SCHEMBL967213 | 0.75 | RXFP1 (0.66) | WEE1KDM4ERXFP1ALDH1A1MAPT | |
| SCHEMBL7013488 | 0.75 | ALDH1A1 (0.55) | KDM4ERXFP1ALDH1A1MAPTLMNA | |
| SCHEMBL7609437 | 0.74 | KDM4E (0.74) | KDM4EALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL7198624 | 0.72 | PRKCI (0.54) | KDM4EALDH1A1MAPTPRKCI | |
| SCHEMBL968341 | 0.71 | KDM4E (0.59) | WEE1KDM4ERXFP1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1323719-A1 | Thienopyrimidine compounds and salts thereof and process for the preparation of the same | NIPPON SODA CO., LTD. (JP) | 2003-07-02 | — | — | EP | disclosed |
| US-6482948-B1 | Thienopyrimidine compounds and salts thereof and process for the preparation of the same | NIPPON SODA CO., LTD. (JP) | 2002-11-19 | — | — | US | disclosed |
| EP-1167367-A1 | THIENOPYRIMIDINE COMPOUNDS AND SALTS THEREOF AND PROCESS FOR THE PREPARATION OF THE SAME | NIPPON SODA CO., LTD. (JP) | 2002-01-02 | — | — | EP | disclosed |