Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.58 |
| ▸ | BRD4 | O60885 | 9/20 | 0.51 |
| ▸ | WEE1 | P30291 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | BRD2 | P25440 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | CDKN1A | P38936 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7199531 | 0.86 | RXFP1 (0.52) | KDM4ERXFP1WEE1ALDH1A1LMNA | |
| SCHEMBL7196501 | 0.83 | WEE1 (0.51) | KDM4ERXFP1WEE1ALDH1A1LMNA | |
| SCHEMBL4506134 | 0.75 | KDM4E (0.57) | KDM4ERXFP1ALDH1A1LMNAMAPT | |
| SCHEMBL969115 | 0.74 | KDM4E (1.00) | KDM4ERXFP1WEE1ALDH1A1LMNA | |
| SCHEMBL7195650 | 0.73 | PRKCI (0.47) | KDM4EWEE1ALDH1A1LMNAMAPT | |
| SCHEMBL13154959 | 0.72 | KDM4E (0.68) | KDM4ERXFP1BRD4ALDH1A1LMNA | |
| SCHEMBL968341 | 0.70 | KDM4E (0.59) | KDM4ERXFP1WEE1ALDH1A1LMNA | |
| SCHEMBL969839 | 0.69 | KDM4E (0.58) | KDM4ERXFP1WEE1ALDH1A1LMNA | |
| SCHEMBL3492144 | 0.69 | ALDH1A1 (0.65) | KDM4ERXFP1ALDH1A1MAPTTSHR | |
| SCHEMBL415023 | 0.69 | MTHFD2 (0.52) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1323719-A1 | Thienopyrimidine compounds and salts thereof and process for the preparation of the same | NIPPON SODA CO., LTD. (JP) | 2003-07-02 | — | — | EP | disclosed |
| US-6482948-B1 | Thienopyrimidine compounds and salts thereof and process for the preparation of the same | NIPPON SODA CO., LTD. (JP) | 2002-11-19 | — | — | US | disclosed |
| EP-1167367-A1 | THIENOPYRIMIDINE COMPOUNDS AND SALTS THEREOF AND PROCESS FOR THE PREPARATION OF THE SAME | NIPPON SODA CO., LTD. (JP) | 2002-01-02 | — | — | EP | disclosed |