Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A1 | P13866 | 3/20 | 0.42 |
| ▸ | SLC5A2 | P31639 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7199059 | 0.92 | SLC5A1 (0.42) | SLC5A1SLC5A2CYP2D6CYP2C19MTNR1A | |
| SCHEMBL7193964 | 0.88 | SLC5A1 (0.44) | SLC5A1SLC5A2MTNR1AMTNR1BAKT1 | |
| SCHEMBL7195025 | 0.86 | SLC5A1 (0.41) | SLC5A1SLC5A2MTNR1AMTNR1BAKT1 | |
| SCHEMBL7198581 | 0.86 | SLC5A1 (0.43) | SLC5A1SLC5A2CYP2D6CYP2C19MTNR1A | |
| SCHEMBL7198557 | 0.86 | MTNR1A (0.48) | SLC5A1SLC5A2MTNR1AMTNR1BTSHR | |
| SCHEMBL7196415 | 0.85 | FOS (0.45) | SLC5A1SLC5A2AKT1TSHRCYP19A1 | |
| SCHEMBL7196497 | 0.85 | LTB4R (0.45) | SLC5A1SLC5A2KMT2AKDM4ENPSR1 | |
| SCHEMBL7187189 | 0.84 | LTB4R (0.47) | KMT2ANPSR1 | |
| SCHEMBL7190189 | 0.83 | SLC5A1 (0.39) | SLC5A1SLC5A2CYP2D6CYP2C19MTNR1A | |
| SCHEMBL7192422 | 0.81 | ABCB1 (0.40) | CYP2D6CYP2C19MTNR1AMTNR1BAKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030065039-A1 | Biologically active 1,3-bis-aromatic-prop-2-en-1-ones, 1,3-bis-aromatic-propan-1-ones, and 1,3-bis-aromatic-prop-2-yn-1-ones | STATENS SERUM INSTITUTE (DK) | 2003-04-03 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030065039-A1 | Biologically active 1,3-bis-aromatic-prop-2-en-1-ones, 1,3-bis-aromatic-propan-1-ones, and 1,3-bis-aromatic-prop-2-yn-1-ones | AKR1C3, AKR1C1, AKR1A1 | SLC5A1 3292/4885SLC5A2 4543/4885CYP2D6 303/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.