SCHEMBL7196902

SCHEMBL7196902

CCOC(=S)N(C)c1ccccc1O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.46
CA2 P00918 2/20 0.46
CA12 O43570 1/20 0.46
CA7 P43166 1/20 0.46
CA9 Q16790 1/20 0.46
CA14 Q9ULX7 1/20 0.46
TSHR P16473 1/20 0.36
GAA P10253 4/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
ATM Q13315 1/20 0.35
PIN1 Q13526 1/20 0.34
SIRT5 Q9NXA8 1/20 0.34
MAPT P10636 5/20 0.33
ALDH1A1 P00352 4/20 0.33
POLB P06746 1/20 0.33
NR1H2 P55055 1/20 0.33
NR1H3 Q13133 1/20 0.33
KDM4E B2RXH2 1/20 0.33
LMNA P02545 1/20 0.33
MEN1 O00255 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7185551 0.80 ALDH1A1 (0.39) CA1CA2CA12CA7CA9
SCHEMBL7194413 0.79 ALDH1A1 (0.38) CA1CA2CA12CA7CA9
SCHEMBL7191106 0.79 CA12 (0.55) CA1CA2CA12CA7CA9
SCHEMBL27816640 0.78 FAAH (0.50) CA1CA2CA12CA9TSHR
SCHEMBL7191152 0.78 ESR1 (0.36) CA1CA2CA12CA7CA9
SCHEMBL7186521 0.73 MAPT (0.44) GAAMAPTALDH1A1KDM4ELMNA
SCHEMBL7183445 0.73 ALDH1A1 (0.40) CA1CA2CA12CA7CA9
SCHEMBL7531399 0.71 CA1 (0.50) CA1CA2CA12CA7CA9
SCHEMBL6821782 0.69 ALDH1A1 (0.39) CA2CA12CA14TSHRGAA
SCHEMBL4174589 0.69 ALDH1A1 (0.39) CA2CA12CA14TSHRGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1304924-A2 COMPOSITIONS FOR REPELLING CRAWLING INSECTS Bayer Aktiengesellschaft (DE) 2003-05-02 EP disclosed
US-20020094993-A1 Compositions for repelling crawling insects S.C. JOHNSON & SON, INC. 2002-07-18 US disclosed
WO-2002005646-A2 COMPOSITIONS FOR REPELLING CRAWLING INSECTS S.C. JOHNSON & SON, INC. (US) (US) 2002-01-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020094993-A1 Compositions for repelling crawling insects ACHE, DDT, GAP43 CA1 1889/4885CA2 1428/4885CA12 3997/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.