Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | FABP4 | P15090 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 4/20 | 0.31 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | HTR2B | P41595 | 2/20 | 0.31 |
| ▸ | MYC | P01106 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7199527 | 0.78 | ADRA2A (0.32) | LMNA | |
| Hydrochloric Acid SCHEMBL6928905 | 0.78 | ADRA2A (0.32) | LMNA | |
| Hydrochloric Acid SCHEMBL7800065 | 0.78 | HTR2C (0.31) | HTR2CHTR2AHTR2B | |
| Hydrochloric Acid SCHEMBL5347487 | 0.73 | MYC (0.37) | HTR2CHTR2AHTR2BMYCLMNA | |
| Hydrochloric Acid SCHEMBL7199981 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL7202409 | 0.69 | NPC1 (0.34) | LMNA | |
| Hydrochloric Acid SCHEMBL7202412 | 0.68 | KDM4E (0.37) | HTR2CLMNA | |
| SCHEMBL27499040 | 0.67 | SLC6A2 (0.38) | SLC6A2SLC6A4SLC6A3HTR2CHTR2A | |
| SCHEMBL4426820 | 0.65 | TSHR (0.50) | MAOAMAOBFABP4MYCLMNA | |
| Hydrochloric Acid SCHEMBL7203977 | 0.65 | ESR1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0776909-B1 | HIGH DENSITY ETHYLENE POLYMER AND METHOD FOR PRODUCING THE SAME | ASAHI CHEMICAL IND (JP) | 2003-11-19 | — | — | EP | disclosed |
| US-5973083-A | HIGH IMPACT RESISTANCE AND HIGH STIFFNESS, EXCELLENT MOLDABILITY, HIGH MELT FLOWABILITY | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1999-10-26 | — | — | US | disclosed |
| EP-0776909-A1 | HIGH-DENSITY ETHYLENIC POLYMER AND PROCESS FOR PRODUCING THE SAME | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1997-06-04 | — | — | EP | disclosed |