Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7199527 | 0.78 | ADRA2A (0.32) | — | |
| Hydrochloric Acid SCHEMBL6928905 | 0.78 | ADRA2A (0.32) | — | |
| Hydrochloric Acid SCHEMBL7202409 | 0.69 | NPC1 (0.34) | — | |
| Ethane SCHEMBL8163438 | 0.68 | GPR3 (0.44) | CYP19A1 | |
| Hydrochloric Acid SCHEMBL7199222 | 0.68 | BCHE (0.32) | — | |
| Hydrochloric Acid SCHEMBL27479364 | 0.68 | PDCD1 (0.32) | ADRB2 | |
| Hydrochloric Acid SCHEMBL618216 | 0.68 | GPR3 (0.42) | CYP19A1 | |
| Hydrochloric Acid SCHEMBL8378993 | 0.66 | GPR3 (0.41) | CYP19A1 | |
| Hydrochloric Acid SCHEMBL8599251 | 0.66 | GPR3 (0.41) | CYP19A1 | |
| Hydrochloric Acid SCHEMBL5352100 | 0.66 | ALDH1A1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0776909-B1 | HIGH DENSITY ETHYLENE POLYMER AND METHOD FOR PRODUCING THE SAME | ASAHI CHEMICAL IND (JP) | 2003-11-19 | — | — | EP | disclosed |
| US-5973083-A | HIGH IMPACT RESISTANCE AND HIGH STIFFNESS, EXCELLENT MOLDABILITY, HIGH MELT FLOWABILITY | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1999-10-26 | — | — | US | disclosed |
| EP-0776909-A1 | HIGH-DENSITY ETHYLENIC POLYMER AND PROCESS FOR PRODUCING THE SAME | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1997-06-04 | — | — | EP | disclosed |