Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.31 |
| ▸ | HTR2A | P28223 | 3/20 | 0.31 |
| ▸ | HTR2B | P41595 | 3/20 | 0.31 |
| ▸ | CD44 | P16070 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7197155 | 0.78 | MAOA (0.31) | HTR2CHTR2AHTR2B | |
| Hydrochloric Acid SCHEMBL7199981 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL5347487 | 0.76 | MYC (0.37) | HTR2CHTR2AHTR2B | |
| Hydrochloric Acid SCHEMBL9422128 | 0.74 | HTR2C (0.32) | HTR2CHTR2AHTR2BCD44CYP1A2 | |
| Hydrochloric Acid SCHEMBL6908390 | 0.74 | HTR2C (0.32) | HTR2CHTR2AHTR2BCD44CYP1A2 | |
| SCHEMBL29458527 | 0.74 | ALDH1A1 (0.35) | HTR2CHTR2AHTR2BCD44CYP1A2 | |
| SCHEMBL7258798 | 0.74 | ALDH1A1 (0.35) | HTR2CHTR2AHTR2BCD44CYP1A2 | |
| Hydrochloric Acid SCHEMBL9422127 | 0.73 | HTR2C (0.31) | HTR2CHTR2AHTR2BCD44CYP1A2 | |
| Hydrochloric Acid SCHEMBL27500337 | 0.73 | HTR2C (0.31) | HTR2CHTR2AHTR2BCD44CYP1A2 | |
| SCHEMBL7621162 | 0.72 | HTR2C (0.33) | HTR2CHTR2AHTR2BCD44CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010041779-A1 | PROCESS FOR MANUFACTURING POLYETHYLENE WITH A FUNCTIONAL END GROUP IN THE PRESENCE OF METALLOCENE CATALYST | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2001-11-15 | — | — | US | disclosed |