Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | PLK1 | P53350 | 1/20 | 0.42 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7197261 | 1.00 | HTT (0.45) | HTTPLK1HAO1TAS1R3TAS1R1 | |
| SCHEMBL7195870 | 0.83 | HTT (0.65) | HTTPLK1HAO1TAS1R3TAS1R1 | |
| SCHEMBL7195875 | 0.83 | HTT (0.65) | HTTPLK1HAO1TAS1R3TAS1R1 | |
| SCHEMBL22550043 | 0.79 | HTT (0.47) | HTTCES2CES1ALDH1A1HPGD | |
| SCHEMBL13808811 | 0.79 | CES2 (0.51) | HTTEPHX2CES2CES1ALDH1A1 | |
| SCHEMBL29249663 | 0.79 | CES2 (0.51) | HTTEPHX2CES2CES1ALDH1A1 | |
| SCHEMBL14429959 | 0.77 | CES2 (0.40) | TAS1R3TAS1R1CES2CES1MAPT | |
| SCHEMBL14431296 | 0.76 | CES2 (0.51) | EPHX2CES2CES1 | |
| SCHEMBL7196791 | 0.75 | L3MBTL1 (0.55) | PLK1HAO1MMP2MMP9MMP8 | |
| SCHEMBL28657562 | 0.75 | TRPA1 (0.39) | HTTCES2CES1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6596445-B1 | Initiators for photopolymerization of radically polymerizable compounds | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-07-22 | — | — | US | disclosed |