Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MPO | P05164 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | WDR5 | P61964 | 1/20 | 0.32 |
| ▸ | RBBP5 | Q15291 | 1/20 | 0.32 |
| ▸ | DPY30 | Q9C005 | 1/20 | 0.32 |
| ▸ | ASH2L | Q9UBL3 | 1/20 | 0.32 |
| ▸ | DOT1L | Q8TEK3 | 3/20 | 0.32 |
| ▸ | SETD2 | Q9BYW2 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Histidine SCHEMBL7197905 | 0.82 | PI4KA (0.51) | CYP3A4SLC7A5CYP1A2ALDH1A1KDM4E | |
| Histidine SCHEMBL3259 | 0.82 | SLC7A5 (0.47) | CYP3A4SLC7A5CYP1A2ALDH1A1KMT2A | |
| Histidine SCHEMBL3258 | 0.82 | SLC7A5 (0.47) | CYP3A4SLC7A5CYP1A2ALDH1A1KMT2A | |
| Histidine SCHEMBL388561 | 0.82 | SLC7A5 (0.47) | CYP3A4SLC7A5CYP1A2ALDH1A1KMT2A | |
| Histidine SCHEMBL995910 | 0.82 | SLC7A5 (0.47) | CYP3A4SLC7A5CYP1A2ALDH1A1KMT2A | |
| Histidine SCHEMBL18824897 | 0.82 | SLC7A5 (0.47) | CYP3A4SLC7A5CYP1A2ALDH1A1KMT2A | |
| Histidine SCHEMBL163443 | 0.82 | SLC7A5 (0.47) | CYP3A4SLC7A5CYP1A2ALDH1A1KMT2A | |
| Histidine SCHEMBL388563 | 0.82 | SLC7A5 (0.47) | CYP3A4SLC7A5CYP1A2ALDH1A1KMT2A | |
| Histidine SCHEMBL163442 | 0.82 | SLC7A5 (0.47) | CYP3A4SLC7A5CYP1A2ALDH1A1KMT2A | |
| Histidine SCHEMBL8080341 | 0.82 | SLC7A5 (0.47) | CYP3A4SLC7A5CYP1A2ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101574151-A | Nutritional food with function of strengthening immunity and preparation method thereof | BEIJING HUIZHONGMINGJIE BIOTEC (CN) | 2009-11-11 | — | — | CN | disclosed |
| US-6590140-B1 | Transgenic plant which expresses a polypeptide comprising given amino acid sequence; iron uptake; can be used to remove pollutants from soil or as nutritional supplements to treat iron- or zinc-deficiency | TRUSTEES OF DARTMOUTH COLLEGE | 2003-07-08 | — | — | US | disclosed |
| US-6162900-A | Metal-regulated transporters and uses therefor | TRUSTEES OF DARTMOUTH COLLEGE (US) | 2000-12-19 | — | — | US | disclosed |
| US-5846821-A | Metal-regulated transporters and uses therefor | TRUSTEES OF DARTMOUTH COLLEGE (US) | 1998-12-08 | — | — | US | disclosed |
| WO-1997045000-A1 | METAL-REGULATED TRANSPORTERS AND USES THEREFOR | TRUSTEES OF DARTMOUTH COLLEGE (US) | 1997-12-04 | — | — | WO | disclosed |
| CN-1123697-A | Bulaogao for preventing senility | HE YANXUE (CN) | 1996-06-05 | — | — | CN | disclosed |