Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 2/20 | 0.51 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.51 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.51 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | XDH | P47989 | 1/20 | 0.51 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | AKT2 | P31751 | 2/20 | 0.35 |
| ▸ | PRKACA | P17612 | 1/20 | 0.35 |
| ▸ | PRKACG | P22612 | 1/20 | 0.35 |
| ▸ | PRKACB | P22694 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Histidine SCHEMBL27713162 | 0.91 | PI4KA (0.42) | PI4KAPI4K2BPI4K2API4KBLMNA | |
| Tryptophan SCHEMBL16670999 | 0.87 | MAPT (0.56) | PI4KAPI4K2BPI4K2API4KBLMNA | |
| Histidine SCHEMBL7197901 | 0.82 | CYP3A4 (0.37) | LMNACYP3A4SLC7A5TSHRCYP1A2 | |
| Histidine SCHEMBL4197034 | 0.81 | SLC7A5 (0.45) | LMNACYP3A4SLC7A5PKMTSHR | |
| Histidine SCHEMBL4197041 | 0.81 | SLC7A5 (0.45) | LMNACYP3A4SLC7A5PKMTSHR | |
| Histidine SCHEMBL32661450 | 0.81 | SLC7A5 (0.45) | LMNACYP3A4SLC7A5PKMTSHR | |
| Histidine SCHEMBL3258 | 0.81 | SLC7A5 (0.47) | LMNACYP3A4SLC7A5PKMTSHR | |
| Histidine SCHEMBL163443 | 0.81 | SLC7A5 (0.47) | LMNACYP3A4SLC7A5PKMTSHR | |
| Histidine SCHEMBL3259 | 0.81 | SLC7A5 (0.47) | LMNACYP3A4SLC7A5PKMTSHR | |
| Histidine SCHEMBL163442 | 0.81 | SLC7A5 (0.47) | LMNACYP3A4SLC7A5PKMTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101574151-A | Nutritional food with function of strengthening immunity and preparation method thereof | BEIJING HUIZHONGMINGJIE BIOTEC (CN) | 2009-11-11 | — | — | CN | disclosed |
| US-6590140-B1 | Transgenic plant which expresses a polypeptide comprising given amino acid sequence; iron uptake; can be used to remove pollutants from soil or as nutritional supplements to treat iron- or zinc-deficiency | TRUSTEES OF DARTMOUTH COLLEGE | 2003-07-08 | — | — | US | disclosed |
| US-6162900-A | Metal-regulated transporters and uses therefor | TRUSTEES OF DARTMOUTH COLLEGE (US) | 2000-12-19 | — | — | US | disclosed |
| US-5846821-A | Metal-regulated transporters and uses therefor | TRUSTEES OF DARTMOUTH COLLEGE (US) | 1998-12-08 | — | — | US | disclosed |
| WO-1997045000-A1 | METAL-REGULATED TRANSPORTERS AND USES THEREFOR | TRUSTEES OF DARTMOUTH COLLEGE (US) | 1997-12-04 | — | — | WO | disclosed |
| CN-1123697-A | Bulaogao for preventing senility | HE YANXUE (CN) | 1996-06-05 | — | — | CN | disclosed |