Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL8750051 | 0.97 | L3MBTL1 (0.47) | L3MBTL1MMP13CYP1A2TAAR1MEN1 | |
| Acetic Acid SCHEMBL7199841 | 0.90 | CYP1A2 (0.44) | CYP1A2TAAR1MEN1KMT2ACTBP2 | |
| Succinic Acid SCHEMBL7197926 | 0.90 | L3MBTL1 (0.48) | L3MBTL1MMP13CYP1A2TAAR1MEN1 | |
| Acetic Acid SCHEMBL8750057 | 0.87 | ACHE (0.46) | MMP13CYP1A2TAAR1MEN1KMT2A | |
| Bromide SCHEMBL7201341 | 0.87 | TAAR1 (0.53) | L3MBTL1MMP13TAAR1MAOB | |
| Hydrochloric Acid SCHEMBL7198118 | 0.87 | TAAR1 (0.53) | L3MBTL1MMP13TAAR1MAOB | |
| Iodide SCHEMBL7197885 | 0.87 | TAAR1 (0.53) | L3MBTL1MMP13TAAR1MAOB | |
| Phosphoric Acid SCHEMBL7197903 | 0.86 | TAAR1 (0.47) | L3MBTL1MMP13TAAR1MEN1KMT2A | |
| Acetic Acid SCHEMBL7192921 | 0.84 | LDHA (0.49) | L3MBTL1MEN1KMT2A | |
| Acetic Acid SCHEMBL7198013 | 0.82 | SNCA (0.44) | L3MBTL1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0624173-B2 | PRECATALYZED CATALYST COMPOSITIONS, PROCESS FOR PREPARING RESINS | DOW CHEMICAL CO (US) | 2003-04-09 | — | — | EP | disclosed |
| EP-0624173-B1 | PRECATALYZED CATALYST COMPOSITIONS, PROCESS FOR PREPARING RESINS | DOW CHEMICAL CO (US) | 1997-04-02 | — | — | EP | disclosed |
| EP-0624173-A1 | PRECATALYZED CATALYST COMPOSITIONS, PROCESS FOR PREPARING RESINS. | DOW CHEMICAL CO (US) | 1994-11-17 | — | — | EP | disclosed |
| US-5360886-A | Alklyphenylphosphine or phosphonium catalyst | THE DOW CHEMICAL COMPANY (US) | 1994-11-01 | — | — | US | disclosed |
| US-5310853-A | Epoxy resins | THE DOW CHEMICAL COMPANY (US) | 1994-05-10 | — | — | US | disclosed |
| WO-1993015126-A1 | PRECATALYZED CATALYST COMPOSITIONS, PROCESS FOR PREPARING RESINS | THE DOW CHEMICAL COMPANY (US) | 1993-08-05 | — | — | WO | disclosed |
| US-5202407-A | Phosphonium or phosphine catalyst having at least three alkylphenyl groups attached to phosphorus atom | THE DOW CHEMICAL COMPANY (US) | 1993-04-13 | — | — | US | disclosed |