Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL8750051 | 0.92 | L3MBTL1 (0.47) | L3MBTL1MMP13TAAR1MEN1KMT2A | |
| Acetic Acid SCHEMBL7197934 | 0.90 | L3MBTL1 (0.46) | L3MBTL1MMP13TAAR1MEN1KMT2A | |
| Succinic Acid SCHEMBL7199837 | 0.90 | HSD17B2 (0.46) | L3MBTL1MMP13TAAR1MEN1KMT2A | |
| Iodide SCHEMBL7197885 | 0.87 | TAAR1 (0.53) | L3MBTL1MMP13TAAR1MAOB | |
| Bromide SCHEMBL7201341 | 0.87 | TAAR1 (0.53) | L3MBTL1MMP13TAAR1MAOB | |
| Hydrochloric Acid SCHEMBL7198118 | 0.87 | TAAR1 (0.53) | L3MBTL1MMP13TAAR1MAOB | |
| Phosphoric Acid SCHEMBL7197903 | 0.86 | TAAR1 (0.47) | L3MBTL1MMP13TAAR1MEN1KMT2A | |
| Succinic Acid SCHEMBL7192914 | 0.84 | LDHA (0.45) | L3MBTL1MEN1KMT2APKM | |
| Acetic Acid SCHEMBL8750057 | 0.82 | ACHE (0.46) | MMP13TAAR1MEN1KMT2AMAOB | |
| Phosphoric Acid SCHEMBL9318099 | 0.82 | MMP13 (0.43) | L3MBTL1MMP13TAAR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0624173-B2 | PRECATALYZED CATALYST COMPOSITIONS, PROCESS FOR PREPARING RESINS | DOW CHEMICAL CO (US) | 2003-04-09 | — | — | EP | disclosed |
| EP-0624173-A1 | PRECATALYZED CATALYST COMPOSITIONS, PROCESS FOR PREPARING RESINS. | DOW CHEMICAL CO (US) | 1994-11-17 | — | — | EP | disclosed |
| WO-1993015126-A1 | PRECATALYZED CATALYST COMPOSITIONS, PROCESS FOR PREPARING RESINS | THE DOW CHEMICAL COMPANY (US) | 1993-08-05 | — | — | WO | disclosed |