Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGM | P11217 | 12/20 | 0.52 |
| ▸ | PYGL | P06737 | 11/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7125086 | 0.90 | PYGL (0.53) | PYGMPYGLTDP1L3MBTL1TP53 | |
| SCHEMBL6432016 | 0.86 | L3MBTL1 (0.61) | PYGMPYGLTDP1L3MBTL1TP53 | |
| SCHEMBL6435067 | 0.85 | PYGL (0.57) | PYGMPYGLTDP1L3MBTL1TP53 | |
| SCHEMBL6438952 | 0.85 | PYGL (0.56) | PYGMPYGLTDP1L3MBTL1LMNA | |
| SCHEMBL6435759 | 0.84 | PYGL (0.55) | PYGMPYGLTDP1L3MBTL1NPSR1 | |
| SCHEMBL6431255 | 0.82 | LMNA (0.64) | PYGMPYGLTDP1L3MBTL1LMNA | |
| SCHEMBL6430909 | 0.82 | PYGM (0.67) | PYGMPYGLTDP1LMNARAB9A | |
| SCHEMBL6440435 | 0.81 | PYGL (0.51) | PYGMPYGLTDP1L3MBTL1LMNA | |
| SCHEMBL6434133 | 0.80 | POLB (0.66) | PYGMPYGLTDP1LMNAKDM4E | |
| SCHEMBL6432826 | 0.80 | PYGM (0.81) | PYGMPYGLTDP1L3MBTL1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6590118-B1 | Used in treatment of and/or prevention of diabetes, especially non-insulin dependent diabetes (Type 2 diabetes) | NOVO NORDISK A/S (DK) | 2003-07-08 | — | — | US | disclosed |
| EP-1220832-A1 | NOVEL AROMATIC COMPOUNDS | NOVO NORDISK A/S (DK) | 2002-07-10 | — | — | EP | disclosed |
| WO-2001023347-A1 | NOVEL AROMATIC COMPOUNDS | NOVO NORDISK A/S (DK) | 2001-04-05 | — | — | WO | disclosed |