Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.36 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7177956 | 0.78 | CNR1 (0.38) | LMNATP53CYP1A2CYP2C19GFER | |
| SCHEMBL7176742 | 0.78 | CNR1 (0.38) | LMNATP53CYP1A2CYP2C19GFER | |
| SCHEMBL9077036 | 0.72 | NOX1 (0.39) | LMNAABCB1ALDH1A1MAPK1 | |
| SCHEMBL7173487 | 0.71 | GFER (0.41) | LMNACYP1A2CYP2C19GFER | |
| SCHEMBL7173479 | 0.71 | GFER (0.41) | LMNACYP1A2CYP2C19GFER | |
| SCHEMBL8466536 | 0.71 | CYP1A2 (0.35) | LMNATP53CYP1A2CYP2C19GFER | |
| SCHEMBL7473785 | 0.69 | CYP1A2 (0.37) | LMNACYP1A2CYP2C19GFERABCC1 | |
| SCHEMBL7473783 | 0.65 | FKBP1A (0.44) | ABCC1ALDH1A1 | |
| SCHEMBL7464560 | 0.63 | FKBP1A (0.42) | LMNACYP1A2CYP2C19GFERABCC1 | |
| SCHEMBL6571561 | 0.62 | NOX1 (0.38) | LMNATP53ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946190-B1 | METHODS AND COMPOSITIONS FOR STIMULATING NEURITE OUTGROWTH | VERTEX PHARMA (US) | 2003-09-24 | — | — | EP | claimed |