Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | FKBP1A | P62942 | 4/20 | 0.37 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.36 |
| ▸ | FKBP4 | Q02790 | 1/20 | 0.36 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7464560 | 0.93 | FKBP1A (0.42) | CYP1A2CYP2C19FKBP1AABCC1FKBP4 | |
| SCHEMBL7177956 | 0.73 | CNR1 (0.38) | CYP1A2CYP2C19FKBP1AABCC1GFER | |
| SCHEMBL7176742 | 0.73 | CNR1 (0.38) | CYP1A2CYP2C19FKBP1AABCC1GFER | |
| SCHEMBL7473783 | 0.72 | FKBP1A (0.44) | FKBP1AABCC1FKBP4FKBP5TBXAS1 | |
| SCHEMBL8466536 | 0.71 | CYP1A2 (0.35) | CYP1A2CYP2C19FKBP1AABCC1FKBP4 | |
| SCHEMBL7181772 | 0.70 | F10 (0.38) | LMNA | |
| SCHEMBL7176769 | 0.70 | F10 (0.38) | LMNA | |
| SCHEMBL7199842 | 0.69 | LMNA (0.39) | CYP1A2CYP2C19ABCC1GFERLMNA | |
| Timcodar SCHEMBL30929684 | 0.68 | ALDH1A1 (0.36) | LMNA | |
| SCHEMBL8463579 | 0.68 | MAPT (0.35) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1204657-A1 | PIPERIDINE AND PYRROLIDINE DERIVATIVES DISPLAYING NEURONAL ACTIVITY | SCHERING AKTIENGESELLSCHAFT (DE) | 2002-05-15 | — | — | EP | disclosed |
| WO-2001012622-A1 | PIPERIDINE AND PYRROLIDINE DERIVATIVES DISPLAYING NEURONAL ACTIVITY | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-02-22 | — | — | WO | disclosed |