SCHEMBL3864807

SCHEMBL3864807

CC(=O)Oc1cccc(C=O)c1O

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 5/20 0.68
TLR2 O60603 1/20 0.68
TLR1 Q15399 1/20 0.68
TLR6 Q9Y2C9 1/20 0.68
PTGDR2 Q9Y5Y4 1/20 0.46
MAPK1 P28482 1/20 0.46
ALDH1A1 P00352 2/20 0.46
HPGD P15428 2/20 0.46
KDM4E B2RXH2 2/20 0.46
ESR1 P03372 1/20 0.46
ITGB3 P05106 1/20 0.46
ITGA2B P08514 1/20 0.46
HMGB1 P09429 1/20 0.46
TSHR P16473 1/20 0.46
GGT1 P19440 1/20 0.46
PTGS1 P23219 1/20 0.46
PTGS2 P35354 1/20 0.46
BLM P54132 1/20 0.46
NAPRT Q6XQN6 1/20 0.46
HSD17B10 Q99714 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL870959 0.86 ALDH1A1 (0.55) ERN1TLR2TLR1TLR6PTGDR2
SCHEMBL7200176 0.86 TLR2 (0.50) ERN1TLR2TLR1TLR6MAPK1
Benzene SCHEMBL3155472 0.85 ALDH1A1 (0.58) ERN1TLR2TLR1TLR6PTGDR2
SCHEMBL21579710 0.84 ERN1 (0.67) ERN1TLR2TLR1TLR6PTGDR2
SCHEMBL8766243 0.84 KDM4E (0.55) ERN1TLR2TLR1TLR6MAPK1
SCHEMBL5241671 0.84 MAPK1 (0.57) ERN1TLR2TLR1TLR6PTGDR2
SCHEMBL30331767 0.84 ERN1 (0.56) ERN1TLR2TLR1TLR6PTGDR2
SCHEMBL2390071 0.84 ERN1 (0.56) ERN1TLR2TLR1TLR6PTGDR2
SCHEMBL5047419 0.84 ERN1 (0.51) ERN1TLR2TLR1TLR6PTGDR2
SCHEMBL8409471 0.83 ERN1 (0.60) ERN1TLR2TLR1TLR6PTGDR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9230827-B2 Method for forming a resist under layer film and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-01-05 US disclosed
US-9230827-B2 Method for forming a resist under layer film and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-01-05 US disclosed
US-9187510-B2 Light-emitting organic platinum complex, light-emitting material containing this complex and functional device OSAKA UNIVERSITY (JP) 2015-11-17 US disclosed
US-9046764-B2 Resist underlayer film composition, method for producing polymer for resist underlayer film, and patterning process using the resist underlayer film composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-06-02 US disclosed
US-9046764-B2 Resist underlayer film composition, method for producing polymer for resist underlayer film, and patterning process using the resist underlayer film composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-06-02 US disclosed
EP-2816409-A1 Method for forming a resist under layer film and patterning process Shin-Etsu Chemical Co., Ltd. (JP) 2014-12-24 EP disclosed
US-20140335692-A1 METHOD FOR FORMING A RESIST UNDER LAYER FILM AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-11-13 US disclosed
US-20140335692-A1 METHOD FOR FORMING A RESIST UNDER LAYER FILM AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-11-13 US disclosed
US-8853031-B2 Resist underlayer film composition and patterning process using the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-10-07 US disclosed
US-8853031-B2 Resist underlayer film composition and patterning process using the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-10-07 US disclosed
US-7592498-B2 Metathesis catalysts LANXESS DEUTSCHLAND GMBH (DE) 2009-09-22 US disclosed
US-7592498-B2 Metathesis catalysts LANXESS DEUTSCHLAND GMBH (DE) 2009-09-22 US disclosed
US-7592498-B2 Metathesis catalysts LANXESS DEUTSCHLAND GMBH (DE) 2009-09-22 US disclosed
US-20080139861-A1 Metathesis catalysts ARLANXEO DEUTSCHLAND GMBH (DE) 2008-06-12 US disclosed
US-20080139861-A1 Metathesis catalysts ARLANXEO DEUTSCHLAND GMBH (DE) 2008-06-12 US disclosed
US-20080139861-A1 Metathesis catalysts ARLANXEO DEUTSCHLAND GMBH (DE) 2008-06-12 US disclosed
EP-1394190-B1 Metathesis catalysts SALTIGO GMBH (DE) 2007-01-03 EP disclosed
EP-1394190-B1 Metathesis catalysts SALTIGO GMBH (DE) 2007-01-03 EP disclosed
US-20040087438-A1 Metathesis catalysts ARLANXEO DEUTSCHLAND GMBH (DE) 2004-05-06 US disclosed
EP-1394190-A1 Metathesis catalysts Bayer Chemicals AG (DE) 2004-03-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080139861-A1 Metathesis catalysts PPOX, PIN4, ICMT ERN1 2687/4885TLR2 4168/4885TLR1 3767/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.