Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.67 |
| ▸ | CA1 | P00915 | 3/20 | 0.67 |
| ▸ | MMP1 | P03956 | 1/20 | 0.67 |
| ▸ | MMP2 | P08253 | 1/20 | 0.67 |
| ▸ | MMP9 | P14780 | 1/20 | 0.67 |
| ▸ | MMP8 | P22894 | 1/20 | 0.67 |
| ▸ | MMP13 | P45452 | 1/20 | 0.67 |
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.50 |
| ▸ | ELANE | P08246 | 1/20 | 0.50 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.49 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.49 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5281032 | 0.88 | MMP8 (0.62) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL603914 | 0.83 | CA1 (0.62) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL28254609 | 0.83 | CA2 (0.61) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL2895067 | 0.80 | MMP1 (0.58) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL6261913 | 0.80 | CA1 (0.58) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL10656290 | 0.80 | CA1 (1.00) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL813026 | 0.80 | CA2 (0.68) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL6492175 | 0.79 | CA1 (0.68) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL5320468 | 0.79 | MMP1 (0.56) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL6293524 | 0.78 | CA2 (0.61) | CA2CA1MMP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0929603-B1 | PLASTICISED POLYMER COMPOSITIONS | UCB SA (BE) | 2003-12-03 | — | — | EP | disclosed |
| US-6624218-B2 | A blend comprising aromatic plasticizer benzenesulphonamides and semi-crystalline polymer; exhibits a processing temperature equal to or greater than 220 degrees C.; melt material for extrusion and injection molding | UCB, S.A. (BE) | 2003-09-23 | — | — | US | disclosed |
| US-20020165301-A1 | Plasticized polymer compositions | UCB, S.A. | 2002-11-07 | — | — | US | disclosed |
| US-6384115-B1 | Plasticized polymer compositions | UCB, S.A. (BE) | 2002-05-07 | — | — | US | disclosed |
| EP-0929603-A1 | PLASTICISED POLYMER COMPOSITIONS | UCB, S.A. (BE) | 1999-07-21 | — | — | EP | disclosed |
| WO-1998014513-A1 | PLASTICISED POLYMER COMPOSITIONS | UCB, S.A. (BE) | 1998-04-09 | — | — | WO | disclosed |
| EP-0322779-A2 | Benzolactam compounds and pharmaceutical uses thereof | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1989-07-05 | — | — | EP | disclosed |
| US-4764570-A | MODIFYING MELAMINE-FORMALDEHYDE RESINS | CASSELLA AKTIENGESELLSCHAFT (DE) | 1988-08-16 | — | — | US | disclosed |