Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 3/20 | 0.49 |
| ▸ | CTSS | P25774 | 3/20 | 0.49 |
| ▸ | CTSK | P43235 | 3/20 | 0.49 |
| ▸ | CTSH | P09668 | 1/20 | 0.49 |
| ▸ | MC4R | P32245 | 1/20 | 0.47 |
| ▸ | APLNR | P35414 | 2/20 | 0.47 |
| ▸ | F2 | P00734 | 4/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGAV | P06756 | 1/20 | 0.43 |
| ▸ | CALCR | P30988 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7200319 | 1.00 | CTSL (0.49) | CTSLCTSSCTSKCTSHMC4R | |
| SCHEMBL30910841 | 0.93 | CTSL (0.52) | CTSLCTSSCTSKCTSHMC4R | |
| SCHEMBL30366772 | 0.93 | MC4R (0.47) | MC4RF2OPRM1OPRD1CALCRL | |
| SCHEMBL31050545 | 0.89 | MC4R (0.53) | CTSLCTSSCTSKCTSHMC4R | |
| SCHEMBL30015314 | 0.89 | REN (0.53) | APLNR | |
| SCHEMBL30366623 | 0.87 | ACE (0.48) | OPRM1OPRD1CALCRL | |
| SCHEMBL31437190 | 0.87 | CTSL (0.62) | CTSLCTSSCTSKCTSHMC4R | |
| SCHEMBL30456911 | 0.85 | APLNR (0.52) | CTSLCTSSCTSKCTSHAPLNR | |
| SCHEMBL31505801 | 0.84 | CTSL (0.56) | CTSLCTSSCTSKCTSHMC4R | |
| SCHEMBL30969039 | 0.84 | APLNR (0.55) | CTSLCTSSCTSKCTSHAPLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030027760-A1 | Composition and methods to improve neural outcome | ENDOCRINZ LIMITED (NZ) | 2003-02-06 | — | — | US | claimed |
| US-20030027760-A1 | Composition and methods to improve neural outcome | ENDOCRINZ LIMITED (NZ) | 2003-02-06 | — | — | US | disclosed |