SCHEMBL7200319

SCHEMBL7200319

CSCC[C@H](N)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N1CCC[C@H]1C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ CTSL P07711 3/20 0.49
▸ CTSS P25774 3/20 0.49
▸ CTSK P43235 3/20 0.49
▸ CTSH P09668 1/20 0.49
▸ MC4R P32245 1/20 0.47
▸ APLNR P35414 2/20 0.47
▸ F2 P00734 4/20 0.44
▸ OPRM1 P35372 1/20 0.43
▸ OPRD1 P41143 1/20 0.43
▸ CALCRL Q16602 1/20 0.43
▸ ITGB3 P05106 1/20 0.43
▸ ITGAV P06756 1/20 0.43
▸ CALCR P30988 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7200318 1.00 CTSL (0.49) CTSLCTSSCTSKCTSHMC4R
SCHEMBL30910841 0.93 CTSL (0.52) CTSLCTSSCTSKCTSHMC4R
SCHEMBL30366772 0.93 MC4R (0.47) MC4RF2OPRM1OPRD1CALCRL
SCHEMBL31050545 0.89 MC4R (0.53) CTSLCTSSCTSKCTSHMC4R
SCHEMBL30015314 0.89 REN (0.53) APLNR
SCHEMBL30366623 0.87 ACE (0.48) OPRM1OPRD1CALCRL
SCHEMBL31437190 0.87 CTSL (0.62) CTSLCTSSCTSKCTSHMC4R
SCHEMBL30456911 0.85 APLNR (0.52) CTSLCTSSCTSKCTSHAPLNR
SCHEMBL31505801 0.84 CTSL (0.56) CTSLCTSSCTSKCTSHMC4R
SCHEMBL30969039 0.84 APLNR (0.55) CTSLCTSSCTSKCTSHAPLNR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 248 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250367192-A1 BICYCLIC COMPOUNDS AND METHODS FOR THEIR USE IN TREATING PITT HOPKINS SYNDROME NEUREN PHARMACEUTICALS LTD (NZ) 2025-12-04 — — US claimed
US-12472177-B2 Bicyclic compounds and methods for their use in treating Pitt Hopkins syndrome NEUREN PHARMACEUTICALS LIMITED (NZ) 2025-11-18 — — US claimed
US-20250312463-A1 AUGMENTED PEPTIDE COMPOSITIONS AND METHODS Neo7Bioscience, Inc. (US) 2025-10-09 — — US claimed
CN-120198276-A Image cartoon style migration method and system based on Puff-Net 南京邮电大学 2025-06-24 — — CN claimed
CN-119919641-A Method for extracting morphological and phenotypic information of plant 安徽农业大学 2025-05-02 — — CN claimed
CN-119904101-A Method for dynamically evaluating critical rainfall of ponding point and predicting ponding risk 合肥泽众城市智能科技有限公司 2025-04-29 — — CN claimed
US-20250127843-A1 ADRENOCORTICOTROPIC HORMONE PEPTIDE COMPOSITIONS AND METHODS OF USE FERRING B.V. (NL) 2025-04-24 — — US claimed
CN-119784234-A Natural resource project budget management system based on performance big data 安徽省第二测绘院 2025-04-08 — — CN claimed
CN-119514252-A Efficient structure optimization method for improving energy storage density of flywheel rotor 南京工业大学 2025-02-25 — — CN claimed
WO-2025037993-A1 DOSAGE FORM FOR PEPTIDE AGENTS MAJEWSKI FILIP (PL) 2025-02-20 — — WO claimed
CN-115345366-A Moderate-level cooperative control method for pedestrian flow of large passenger transport hub 宁波工程学院 2022-11-15 — — CN claimed
CN-115243688-A Bicyclic compounds and methods of their use in treating PITT HOPKINS syndrome 诺仁制药有限公司 2022-10-25 — — CN claimed
CN-115000969-A Hybrid power flow controller planning configuration method considering wind power integration 国网河北省电力有限公司经济技术研究院 2022-09-02 — — CN claimed
EP-4048264-A1 BICYCLIC COMPOUNDS AND METHODS FOR THEIR USE IN TREATING PITT HOPKINS SYNDROME Neuren Pharmaceuticals Limited (NZ) 2022-08-31 — — EP claimed
CN-110350548-B UPFC-based power system safety and stability online prevention control method, device and system 国电南瑞科技股份有限公司 2022-08-30 — — CN claimed
WO-2022173315-A1 TREATMENTS OF PRADER-WILLI SYNDROME NEUREN PHARMACEUTICALS LIMITED (NZ) 2022-08-18 — — WO claimed
US-11378073-B2 Estimation device and valve control device SHIMADZU CORPORATION (JP) 2022-07-05 — — US claimed
CN-112862259-B Development and evaluation method for three-dimensional exploitation of sea-land transition phase shale reservoir 西南石油大学 2022-07-01 — — CN claimed
CN-114384610-A Hail short-term landing area forecasting method and device, electronic equipment and storage medium 中国人民解放军94201部队 2022-04-22 — — CN claimed
US-20030027760-A1 Composition and methods to improve neural outcome ENDOCRINZ LIMITED (NZ) 2003-02-06 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250367192-A1 BICYCLIC COMPOUNDS AND METHODS FOR THEIR USE IN TREATING PITT HOPKINS SYNDROME QPCT, GRIA2, GGPS1 CTSL 2352/4885CTSS 3168/4885CTSK 3044/4885
US-20250127843-A1 ADRENOCORTICOTROPIC HORMONE PEPTIDE COMPOSITIONS AND METHODS OF USE MC2R, CRH, NR5A1 CTSL 2881/4885CTSS 4787/4885CTSK 4555/4885
US-12472177-B2 Bicyclic compounds and methods for their use in treating Pitt Hopkins syndrome QPCT, GRIA2, GGPS1 CTSL 2352/4885CTSS 3168/4885CTSK 3044/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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