Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.36 |
| ▸ | HTR2A | P28223 | 6/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4907724 | 0.79 | HTR2A (0.39) | TAAR1HTR2ATRPA1CES2CES1 | |
| SCHEMBL10914666 | 0.78 | TAAR1 (0.53) | TAAR1HTR2ATRPA1SLC6A2SLC6A4 | |
| SCHEMBL5973390 | 0.78 | HTR2A (0.53) | HTR2AHRH1LMNASLC6A2SLC6A4 | |
| SCHEMBL7206943 | 0.77 | ALDH1A1 (0.41) | LMNATDP1 | |
| SCHEMBL5852562 | 0.77 | TAAR1 (0.50) | TAAR1HTR2ATRPA1 | |
| SCHEMBL22325539 | 0.77 | CYP2C19 (0.37) | TAAR1HTR2ATRPA1HRH1LMNA | |
| SCHEMBL5852566 | 0.77 | TAAR1 (0.50) | TAAR1HTR2ATRPA1 | |
| SCHEMBL22325537 | 0.77 | CYP2C19 (0.37) | TAAR1HTR2ATRPA1HRH1LMNA | |
| SCHEMBL7855317 | 0.75 | LMNA (0.54) | LMNA | |
| SCHEMBL17763415 | 0.74 | CES2 (0.41) | TAAR1HTR2ATRPA1CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003051118-A1 | PESTICIDAL ACTIVITY OF FUNCTIONALIZED CYCLOPROPANES | NORTH CAROLINA STATE UNIVERSITY (US) | 2003-06-26 | — | — | WO | disclosed |
| EP-1241941-A2 | PESTICIDAL ACTIVITY OF FUNCTIONALIZED ALKENES | NORTH CAROLINA STATE UNIVERSITY (US) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001041543-A2 | PESTICIDAL ACTIVITY OF FUNCTIONALIZED ALKENES | NORTH CAROLINA STATE UNIVERSITY (US) | 2001-06-14 | — | — | WO | disclosed |