SCHEMBL7206943

SCHEMBL7206943

C/C=C/CC(Br)c1ccc(OC)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.41
TSHR P16473 3/20 0.41
TP53 P04637 2/20 0.41
CYP3A4 P08684 2/20 0.41
LMNA P02545 1/20 0.41
KDM4E B2RXH2 1/20 0.41
AOC3 Q16853 3/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C19 P33261 1/20 0.40
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA7 P43166 1/20 0.39
CA9 Q16790 1/20 0.39
CA14 Q9ULX7 1/20 0.39
MAPK1 P28482 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
SLC2A1 P11166 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7200468 0.77 TAAR1 (0.36) LMNATDP1
SCHEMBL3606244 0.75 MIF (0.49) ALDH1A1TSHRAOC3CYP1A2CYP2D6
SCHEMBL10481598 0.75 CA12 (0.48) ALDH1A1TSHRAOC3CYP1A2CYP2D6
SCHEMBL6981462 0.73 TSHR (0.52) ALDH1A1TSHRAOC3CYP1A2CYP2D6
SCHEMBL31634221 0.72 AOC3 (0.56) ALDH1A1TSHRTP53CYP3A4AOC3
SCHEMBL9772487 0.72 CA12 (0.44) ALDH1A1TSHRAOC3CYP1A2CYP2D6
SCHEMBL27376923 0.70 CA12 (0.42) ALDH1A1TSHRAOC3CYP1A2CYP2D6
SCHEMBL9425364 0.69 CA1 (0.58) ALDH1A1TSHRCYP3A4KDM4EAOC3
SCHEMBL119132 0.69 CA1 (0.58) ALDH1A1TSHRCYP3A4KDM4EAOC3
SCHEMBL6682760 0.69 MMP13 (0.44) ALDH1A1TSHRAOC3CYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003051118-A1 PESTICIDAL ACTIVITY OF FUNCTIONALIZED CYCLOPROPANES NORTH CAROLINA STATE UNIVERSITY (US) 2003-06-26 WO disclosed
WO-2002098220-A2 PESTICIDAL ACTIVITY OF FUNCTIONALIZED ALKENES NORTH CAROLINA STATE UNIVERSITY (US) 2002-12-12 WO disclosed
EP-1241941-A2 PESTICIDAL ACTIVITY OF FUNCTIONALIZED ALKENES NORTH CAROLINA STATE UNIVERSITY (US) 2002-09-25 EP disclosed
WO-2001041543-A2 PESTICIDAL ACTIVITY OF FUNCTIONALIZED ALKENES NORTH CAROLINA STATE UNIVERSITY (US) 2001-06-14 WO disclosed