Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.46 |
| ▸ | BHMT | Q93088 | 10/20 | 0.44 |
| ▸ | BHMT2 | Q9H2M3 | 1/20 | 0.44 |
| ▸ | NOS2 | P35228 | 3/20 | 0.41 |
| ▸ | NOS3 | P29474 | 2/20 | 0.41 |
| ▸ | NOS1 | P29475 | 2/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.39 |
| ▸ | FNTA | P49354 | 1/20 | 0.38 |
| ▸ | FNTB | P49356 | 1/20 | 0.38 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | THPO | P40225 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methionine SCHEMBL12096907 | 0.93 | RNPEP (0.52) | RNPEPBHMTBHMT2NOS2NOS3 | |
| Methionine SCHEMBL1610240 | 0.93 | RNPEP (0.52) | RNPEPBHMTBHMT2NOS2NOS3 | |
| Racemethionine SCHEMBL2418302 | 0.93 | RNPEP (0.52) | RNPEPBHMTBHMT2NOS2NOS3 | |
| Methionine SCHEMBL6045795 | 0.91 | RNPEP (0.50) | RNPEPBHMTBHMT2NOS2NOS3 | |
| Methionine SCHEMBL2260610 | 0.91 | BHMT (0.50) | RNPEPBHMTBHMT2NOS2NOS3 | |
| Racemethionine SCHEMBL2260603 | 0.91 | BHMT (0.50) | RNPEPBHMTBHMT2NOS2NOS3 | |
| Racemethionine SCHEMBL27691481 | 0.91 | BHMT (0.50) | RNPEPBHMTBHMT2NOS2NOS3 | |
| Methionine SCHEMBL8450225 | 0.88 | PTGS1 (0.55) | RNPEPBHMTBHMT2NOS2NOS3 | |
| Racemethionine SCHEMBL8450224 | 0.88 | PTGS1 (0.55) | RNPEPBHMTBHMT2NOS2NOS3 | |
| Methionine SCHEMBL3883236 | 0.86 | BHMT (0.50) | RNPEPBHMTBHMT2NOS2NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610270-B1 | Determining the rate of substrate-product conversion for gateway enzymes important to therapy management, using labelled metaprobes | XANTHUS LIFE SCIENCES, INC. | 2003-08-26 | — | — | US | disclosed |
| US-6284219-B1 | ADMINISTERING LABELLED TRACER PROBE, SPECIFICALLY DESIGNED SUBSTRATE OF GATEWAY ENZYME, TO MAMMALIAN SUBJECT, MEASURING LABELLED PRODUCT OF ENZYME ACTION TO DETERMINE EXTENT OF CONVERSION | PHENOME SCIENCES INC. | 2001-09-04 | — | — | US | disclosed |
| EP-1089765-A2 | $i(IN VIVO) DETERMINATION OF METABOLIC FUNCTION FOR USE IN THERAPY MANAGEMENT | Phenome Sciences Inc. (US) | 2001-04-11 | — | — | EP | disclosed |
| WO-2000000636-A2 | IN VIVO DETERMINATION OF METABOLIC FUNCTION FOR USE IN THERAPY MANAGEMENT | PHENOME SCIENCES INC. (US) | 2000-01-06 | — | — | WO | disclosed |