Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6650061 | 0.90 | SMN1; SMN2 (0.42) | THRBKMT2AMEN1HSD17B10ALOX15 | |
| SCHEMBL6643832 | 0.90 | NAMPT (0.42) | THRBKMT2AHSD17B10ALOX15RAB9A | |
| SCHEMBL6642961 | 0.89 | THRB (0.38) | THRBKMT2AHSD17B10ALOX15RAB9A | |
| SCHEMBL6647472 | 0.89 | THRB (0.43) | THRBKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL6645501 | 0.88 | LMNA (0.47) | THRBHIF1AMAPTLMNAPTGDR2 | |
| SCHEMBL6646119 | 0.87 | THRB (0.40) | THRBKMT2AMEN1HSD17B10ALOX15 | |
| SCHEMBL6649808 | 0.85 | THRB (0.43) | THRBKMT2AMEN1HSD17B10ALOX15 | |
| SCHEMBL7201171 | 0.83 | SCD (0.43) | KMT2ARAB9AALDH1A1MAPTTDP1 | |
| SCHEMBL6644554 | 0.82 | ALDH1A1 (0.45) | THRBKMT2AHSD17B10ALOX15RAB9A | |
| SCHEMBL6644406 | 0.82 | THRB (0.53) | THRBHSD17B10RAB9ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004039795-A2 | AMIDE COMPOUNDS FOR THE TREATMENT OF HYPERLIPIDEMIA | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-05-13 | — | — | WO | disclosed |